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1、复方阿嗪米特肠溶片联合莫沙比利治疗胆源性消化不良的疗效观察杨建军1梁静21秦皇岛市第三医院河北秦皇岛066000;2山海关人民医院河北秦皇岛066001【摘要】目的:评估复方阿嗪米特肠溶片联合莫沙比利治疗胆源性消化不良的疗效和安全性。方法:将胆源性消化不良患者82例随机分成2组，观察组42例，对照组40例。观察组给予复方阿嗪米特肠溶片2片，3次/d,莫沙比利5mg,3次/d。疗程2周。对照组给予胆维他片25mg,3次/d,疗程2周。观察治疗前后腹胀等症状积分改善率及有效率。结果:复方阿嗪米特肠溶片联合莫沙比利治疗后症状总积分为18±09分，有效率952%,明显高于对照组P
2、<001。结论:复方阿嗪米特肠溶片联合莫沙比利治疗胆源性消化不良是一种安全有效的药物。【关键词】消化不良;胆源性；复方阿嗉米特；莫沙比利；胆维他Compoundazintamideenteric-coatedtabletscombinedwithMosaBillyclinicalobservationonthetreatmentofgallstonedyspepsiaYangJianjunLiangJing(TheThirdHospitalofQinhuangdaoCity,HebeiQinhuangdao,066000;Shanhaiguanpeople'sHospital,Hebe
3、iQinhuangdao,066000)【Abstract】Objective:assessmentofcompoundooxazinemiltenteric-coatedmetforminhydrochloridewithmoserBillytherapyefficacyandsafetyofgallstoneindigestion.Methods82patientswithgallstoneindigestionwererandomlydividedinto2groups,theobservationgroup,42cases,controlgroup40cases.Observa
4、tiongroupwasgivencompoundoxazineo2slicesmiltenteric-coatedmetforminhydrochloride,3times/day,moserBilly5mg,3times/day.Treatmentfor2weeks.Thecontrolgroupgivenbraverydimensionhe25mg,3times/day,treatmentcourse2weeks.Wereobservedbeforeandaftertreatmentofabdominaldistensionandothersymptomsintegralperi
5、odandefficient.Resultscompoundooxazinemiltenteric-coatedmetforminhydrochloridecombinedmoserBillysymptomsaftertreatmentthetotalscoreof18±09points,effectiveratewas952%,significantlyhigherthanthecontrolgroupP<005).Conclusioncompoundooxazinemiltenteric-coatedmetforminhydrochloridecombinedt
6、herapywithmoserBillygallstoneindigestionisasafeandeffectivedrug.【KeywordsiDyspepsia;biliary;compoundazintamide;MosaBilly;trithioanethol【中图分类号】R72311【文献标识码】B【文章编号】1674-8999(2013)08-0188-02消化不良从病因上可分为器质性消化不良(OD)和功能性消化不良(FD)。胆源性消化不良是指胆石症，胆囊炎，胆切除术后引起的餐后腹胀，早饱，嗳气,腹泻等。我院自2011年至2012年应用复方阿嗪米特肠溶片联合莫沙比利治疗胆
7、源性消化不良，疗效观察如下。1资料与方法11一般资料：胆源性消化不良患者82例，其中病因构成为胆囊切除术后10例，慢性胆囊炎37例，胆结石27例，胆囊息肉8例。82例患者分为观察组42例，年龄17〜73岁，平均(360±48)岁，男性16例，女性26例；对照组40例，年龄18〜72岁，平均(354±45)岁，男性13例，女性27例。2组年龄，性别构成比，症状类型均具有可比性。12入选与排除标准：①经B超，CT,或ER
