缺血性脑卒中合并卵圆孔未闭患者的临床研究

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1、授予单位代码10089学号或申请号20153221中国图书分类号R743.3HebeiMedicalUniversity硕士学位论文专业学位缺血性脑卒中合并卵圆孔未闭患者的临床研究研究生：董中君导师：许蕾教授专业：神经病学二级学院：河北医科大学第二医院2018年3月目录中文摘要··········································································································1英文摘要·············

2、·····························································································2英文缩写··········································································································4研究论文缺血性脑卒中合并卵圆孔未闭患者的临床研究前言································

3、··········································································5材料与方法······························································································5结果······················································································

4、····················9附图··········································································································11附表··········································································································12讨论····················

5、······················································································16结论··········································································································18参考文献·····························································

6、·····································18综述心源性栓塞导致缺血性脑卒中的相关病因分析······························21致谢··················································································································33个人简历················································

7、··························································34中文摘要缺血性脑卒中合并卵圆孔未闭患者的临床研究摘要目的：研究缺血性脑卒中合并卵圆孔未闭（PFO）患者的临床特点及介入封堵术（TDC）对脑卒中复发的预防作用。方法：选取2014年9月至2017年12月收治于河北医科大学第二医院神经内科的缺血性脑卒中合并卵圆孔未闭患者46例作为研究对象，将46例患者分为<40岁组（22例）和≥40岁组（24例）；46例患者中27例患者有介入封堵术手术指征，其中10例行介入

8、封堵术，其余17例未行介入封堵术。所有患者均行头颅核磁（MRI）、经胸超声心动图声学造影（cTTE）及经食道超声心动图声学造影检查（cTEE），并收集相关临床资料进行回顾性分析；随访出院3个月后有无脑卒中复发。结果：病灶数量、前后脑循环系统、卵圆孔未闭分流量在<40岁组和≥40岁组中差异无统计学意义（P>0.05）；