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1、51例咳嗽变异性哮喘患儿过敏原检测结果分析(上海市奉贤区奉城医院儿科201411)【摘要】目的:通过对咳嗽变异性哮喘过敏原检测结果进行分析,从而为制定咳嗽变异性哮喘过敏原的筛查方案提供指导依据。方法:对2010年1月-2012年1月来我院就诊的51例咳嗽变异性哮喘患儿行过敏原检测,同时分析其中23例CVA患儿治疗前后肺功能指标FEV1、FVC、PEF、FEV1/FVC、FEF25、FEF50、FEF75变化情况。结果:51例咳嗽变异性哮喘患儿中,过敏原阳性以对屋尘过敏者最多,占88.24%,其次为粉尘螨,占82.35%;食物性过
2、敏原中对牛奶过敏最多,占15.69%,其次为对海虾过敏,占9.80%。其中23例咳嗽变异性哮喘患儿行支气管舒张治疗后,FEF25、FEF50、FEF75均较治疗前明显提高,但FEV1、FVC、PEF、FEV1/FVC治疗后较治疗前未见明显变化。结论:对咳嗽变异性哮喘患儿的过敏原进行检测,可以为临床过敏性疾病的诊断和治疗提供依据,同时根据过敏原检测结果应用支气管舒张治疗可以改善患儿的肺功能,具有重要的临床意义和指导作用。【关键词】咳嗽变异性哮喘;过敏原;肺功能【中图分类号】RR725.6【文献标识码】A【文章编号】1004-619
3、4(2015)02-0231-02Theanalysisof51casescoughvariantasthmainchildrenallergentest(201411)LiHengtaoWangGenzaiZhuHongqingZhaJianzhong【Abstract】Objective:Toanalyzetheallergytestingresultsofcoughvariantasthma,soastoprovidethebasisforguidingthedevelopmentofallergenscreeningpr
4、ogram.Methods:FromJanuary2010toJanuary2012inourhospital,51patientswithcoughvariantasthmachildrenunderwentallergytesting,analyzedthelungfunctionbeforeandafterthetreatment,andobservedthechangeofCVAFEV1,FVC,PEF,FEV1/FVC,FEF25,FEF50,FEF75of23caseswithcoughvariantasthmach
5、ildren.Results:51patientswithcoughvariantasthmainchildren,allergenpositivetohousedustallergymost,accountingfor88.24%,followedbydustmites,accountingfor82.35%;foodallergensallergictomilkthemost,accountingfor15.69%followedbyshrimpallergy,accountingfor9.80%.23casesofcoug
6、hvariantasthmainchildrenlinebronchodilatortherapy,FEF25,FEF50,FEF75thanbeforetreatmentsignificantlyimprovedFEV1,FVC,PEF,FEVl/FVCaftertreatmentthanbeforetreatmentnosignificantchange.Conclusion:detectallergenscoughvariantasthmainchildren,canprovidethebasisforthediagnos
7、isandtreatmentofclinicalallergicdisease,sothatchildrenavoidcontactwithpathogenicfactorsleadtotheirownallergies,hasimportantclinicalimplicationsandguidance.【Keywords]coughvariantasthma;allergens;lungfunction咳嗽变异型哮喘(CoughVariantAsthma,CVA)是一种常见的过敏性疾病,由过敏原经吸入或食入等途径进入体内后
8、引起相应IgE类抗体产生并导致的变态反应疾病,对CVA过敏原的测定对临床诊断、治疗和预防具有重要意义[1]。本研宄旨在通过对咳嗽变异性哮喘过敏原检测结果进行分析,从而为制定过敏原筛査方案提供指导依据。1资料与方法1.1一般资料选取2010年1月-2012年1月来