co2超临界和乙醇提取蜂胶对大鼠降血脂效果

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1、第28卷第3期江西农业大学学报Vol.28，No.32006年6月ActaAgriculturaeUniversitatisJiangxiensisJune,2006文章编号:1000一2286(2006)03一0433一03C02超临界和乙醇提取蜂胶对大鼠降血脂效果曾志将’，杨明‘，杨新跃z，周银平气刘志勇2(1.江西农业大学动物科技学院，江西南昌330045;2.江西省劳动卫生职业防治研究所，江西南昌330006)气摘要:试验用健康雄性SD大鼠，给予高脂颗粒饲料喂饲后第9d，大鼠眶静脉取血，测定血清总胆固醇(TC)、甘油三M(TG)和高密度脂蛋白(HDL一

2、C)值。高脂血症动物模型成功后，随机分为对照组1(给予聚乙二薄400)、超临界蜂胶高剂量组(600mg/kgBW)、超临界蜂胶中剂量组(300mg/kgBW)、超临界蜂胶低剂量组(150mg/kgBW);对照组2(给予食用油)、乙醇提取蜂胶高剂量组(600m岁kgBW)、乙醇提取蜂胶中剂量组(300mg/kgBW)、乙醇提取蜂胶低剂量组(150mg/kgBW)8个组。分组后连续4周蜂胶灌胃，同时各组大鼠继续给予高脂颗粒饲料喂饲，之后各组大鼠取血测定TC,TG和HDL一C。结果表明:喂蜂胶28d后，只有超临界蜂胶高剂量组(600m岁kgBW)的TG值和乙醇提取蜂

3、胶高剂盘组(600mg/kgBW)的TC值分别与相对照组差异显著，其它指标都差异不显著。关键词:蜂胶;CO:超临界提取;乙醇提取;降血脂中图分类号:S896.6文献标识码:ATheEffectofPropolisObtainedbyC02SupercriticalExtractionandEthanolExtractiononDecreaseLipoidemiaZENGZhI一Jiangt，YANGMing'，YANGXin一yue2，ZHOUYin一ping2，LIUZhi一ygong2(1.CollegeofAnimalScienceandTechnolo

4、gy，JAU，Nanchang330045，China;2.WorkingSanitationandProfessionPreventionInstituteofJiangxiProvince，Nanchang330006,China)Abstract;HealthymaleSDratswerefedwithhigh一lipidpelletfeedfor9days，thenbloodfromeyepitveinwascollectedtodetectthelevelsofserumTC，TGandHDL一C.Therats.wererandomizedinto

5、8groups.Differentfeedsforeachgroupwerearrangedasfollows:thesupercriticalproplisgroupsincludedthecontrolgroupI(withoutpropolis)，thehighdosegroup(600m盯kgBW),themiddledosegroup(300m酬kgBW)andthelowdosegroup(150mg/kgBW).Thealcoholproplisgroupsincludedthecontrolgroup2(with-outpropolis)，th

6、ehighdosegroup(600mg/kgBW)，themiddledosegroup(300mg/kgBW)andthelowdosegroup(150mg/kgBW).Thentheywerefedwithpropolisandhigh一lipidpelletfeedinthemeantimefor4weeks.Thebloodwascollectedonthe28thdayafterfedwithpropolisandthelevelsofserumTC，TGandHDL一Cweredetected.Theresultshowedthattheeff

7、ectofhighdosesupercriticalpropolis(600mg/kgBW)ondecreasingthecontentofserumTGandthatofhighdosealcoholpropolis(600mg/kgBW)ondecrea-singthecontentofserumTCinratsweresignificant,comparedwiththecontrolgroupsrespectively，buttheother'indexeswerenot.Keywords:propolis;CO,supercriticalextrac

8、tion;ethanolextract