膝骨关节炎关节液蛋白多糖的变化与中医辨证施治影响随机分组对照

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1、万方数据中国组织工程研究与l临床康复第J2誊第2DJ锣2008—05—13出版JournalofClinicalRehabilitative71ssueEngineeHngResearchMayl3，2008V01．12，No．20膝骨关节炎关节液蛋白多糖的变化与中医辨证施治影响：随机分组对照：l：张洪美1，闵重函1，张志强1，李辉1，荆琳2，朝浩鹏1，李延伟1EffectofChinesemedicinetreatmentaccordingtosyndromedifferentiationonproteoglycanlevelsinthesynovialfluidofk

2、neeosteoarthritis：RandomizedcontrolstudyZhangHong．meil，MinZhong．hanl，ZhangZhi-qian91，LiHuil，JingLin2，ChaoHao-pen91，LiYan·weil1FirstDepartmentofBoneandJoint,WangjingHospital，ChinaAcademyofChineseMedicalSciences．Beijing100102．China；‘DepartmentofBoneTraumamlogy．HuairouCourttyHospitalofTradit

3、ionalChineseMedicine，Beijing101400，China2■angHong—mei，Chiefphysician．Profe$sor,FirstDepartmentofBOneandJoint,WangjingHospital，ChinaAcademyofChineseMedicalSciences．Beijing100102，Chinawangjingzhm@stha．tomSupportedby：thePredominantDisnas￡TopicoftheStateAdministrationofTraditionalChineseMedic

4、ine”1hditionalChine∞MedicincStandardizationofKneeOsteoarthritisDiagnosisandTreatment”．No．CACMS05Y～—0030’AbstractAIM：Levelchangesofproteoglycan(PGlinthesynovialfluidisanindicatorofcartilaginousaffectionbystages．nlisstudywasdesignedtoevaluatetheeffectofChinesemedicinetreatmentaccordingtosyn

5、dromedifferentiationontllePGintIlesynovialfluidofkneeosteoarthritis．METHoDS：FromDecember2006t0March2007．sixtypatientswithkneeosteoa_qhdtisadmittedintheOutpatientDepartmentofOrthopaedics，Wan自ingHospital，ChinaAcademyofChineseMedicalSciences，weredividedintotreatmentgroup(n=32，meanage47．1year

6、s)andcontrolgroup(n=28，meanage48．7years)byrandom．mtreatmentgroupwasconsistedbythreeChinesediseasemodels．1lcaseswithdeflciencyofliverandkidneyandstasisoftendonsandvessels(modelA)，13caseswithinsufficiencyofspleenandkidneyanddampnessinfusionintoboneandjoints(modelB)，and8caseswithinsufficienc

7、yofliverandkidneyandobstructionofchannelsbyphlegm(modelC)．T11etreatmentgrouptookChinesemedicineparticlesorally，oneadministrationperday，totally3months；AmodelwastreatedwithLiuweiDihuangTang(consistingofShudi，HuaishanyaoandFuling，etc)；BmodelwastreatedwithChushiTongbiTa