改良序贯疗法根除标准三联治疗法失败的幽门螺杆菌的疗效观察论文

《改良序贯疗法根除标准三联治疗法失败的幽门螺杆菌的疗效观察论文》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、10114GXJS1008TheEffectsofImprovedSequentialTherapyEradicateHelicobacterpyloriinTripleTherapyafterFailure···············································································································································································…………………………………………………

2、…….1………………………………………………………………...2…………………………………………………….4................................................................................................8……………………………………………………………….11……………………………………………………………….15…………………………………………………………...16………………………………………………………………...20…………………………………………………………...31…………………………

3、…………………………………………37………………………………………………………………38……………………………………………………………………39HelicobacterpyloriHpHpHp20mgBid+1.0gBid+0.5gBid1010020mgBid+1.0gBid20mgBid+400mgQd+0.4gTid20mgBid+220mgBid+0.5gBid+0.4gBid10PPI14C-HpHpSPSS16.O2P<0.05(1)94.23%ITTPP90.74%79.07%ITT73.91%PPP<0.05(2)

4、(3)P<0.05I5.56%19.57%3.353.42HpIITheEffectsofImprovedSequentialTherapyEradicateHelicobacterpyloriinTripleTherapyafterFailureAbstractPurposeThisstudywastoevaluatetheclinicalefficacyandsafetyoftheimprovedsequentialtherapywithMoxifloxacinfortheHelicobacterpylori(Hp)whichafterthefailuretreatmentof

5、standardtripleandquadrupletherapy.Thepurposeistoseekingahigher,saferandbetterpatientcomplianceeradicatedtreatmentforHelicobacterpylori.MethodsTheobserversofthisstudyarethepatientswhohaddiagnosedofHpinfectioninTaiyuanCentralHospitalandacceptstandardtriple(theNexium20mgBid+Amoxycillin1.0gBid+Clarith

6、romycin0.5gBidcourseof10days)indepartmentofGastroenterologytertiaryhospitalsbuthadfailedalready.Inaccordancewithinclusioncriteriatoselectthestandardtripletherapyfailed100patientswererandomlydividedintotwogroups,fivedayspriortothesequentialtherapytreatmentgroupreceivedNexium20mgBid+Amoxycillin1.0gB

7、id,fivedaysafterNexium20mgBid+Moxifloxacin400mgQd+Metronidazole0.4gTidsequentialtherapy;controlgroupreceivedNexium20mgBid+bismuthpotassiumcitrate220mgBid+Clarithromycin0.5gBid+Metronidazole0.4gBidquadrupletherapy