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1、Lowvisionaidinexudativemaculardegenerationtreatedbyphotodynamictherapyandthermallaserphotocoagulation×÷ÕߣºMonteroJA,Ruiz-MorenoJM,Sanchez-deCastroMJ,FabianiC¡¾ÕªÒª¡¿Todeterminetheefficacyoflowvisionrehabilitation(LVR)inpatientswithagerelatedmaculardegeneration(AMD)treatedbyphotodynamictherapy(PDT)c
2、omparedtothosetreatedbythermallaser(TLP).METHODS:Aretrospectivestudywasperformedexaminingthefilesof42patients(42eyes)withAMDwhohadbeentreatedeitherbyTLP(Group1)andPDT(Group2).OnceAMDwasconsideredtobeinactivetheyunderwentvisualrehabilitationintheLVRUnitinordertoincreasetheirabilityfordistantandnearvi
3、sion.RESULTS:EighteeneyeshadreceivedPDTand24hadreceivedTLP.Averagecorrectedvisualacuityafterlasertherapywas0.14inGroup1,and0.16inGroup2.Nostatisticallysignificantdifferenceswerefoundbetweenbothgroupsbeforeandafterlasertherapy.BothgroupsshowedimprovementafterLVR;however,13statisticallysignificantdiff
4、erencesbetweenbothgroupswerefoundonlyfornearvision.CONCLUSION:OurfindingssuggestthateventhoughbothPDTandTLPareassociatedtoadecreasedvisualacuityaftertreatment,LVRmaybemoresuccessfulfornearvisionamongpatientstreatedbyPDT¡¾¹Ø¼ü´Ê¡¿agerelatedmaculardegenerationMonteroJA,Ruiz-MorenoJM,Sanchez-deCastroMJ
5、,FabianiC.Lowvisionaidinexudativemaculardegenerationtreatedbyphotodynamictherapyandthermallaserphotocoagulation.IntJOphthalmol(GuojiYankeZazhi),2006;6(2):298-301INTRODUCTIONAgerelatedmaculardegeneration(AMD)isoneoftheleadingcausesofvisionlossindevelopedcountriesinelderlypopulation[1].Differenttherap
6、euticalapproacheshavebeenattempted,suchasthermallaserphotocoagulation(TLP)[2,3],transpupillarythermotherapy[4,5],photodynamictherapy(PDT)[6],maculartranslocation[7]andantiangiogenic13drugs[8].However,eventhoughthetreatmentmaybesuccessfultoclosethechoroidalneovascularization(CNV),itisnotalwaysassocia
7、tedtoanimprovementinvisualacuity(VA)becauseoftherecurrencesofCNVandthepersistenceofcentralscotoma[6,9].Lowvisionrehabilitation(LVR)hasbeendevelopedtoimprovelifequalityinpatientswithVAunder20/60.LVRinc