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1、LHRH类似物在卵巢癌治疗中的应用国外医学妇幼保健分册2003年第14卷第6期413果;④所需剂量小;③对mdrl,LRP,Topo-1I的作用有同步性.TNF在Esherichacoli中克隆成功使TNF有可能应用于临床实验和治疗癌症.但其副作用:发热寒战,乏力不适,恶心呕吐,胸痛等限制了其临床应用.目前以低剂量rHuT—NF联合化疗药是卵巢癌研究方向之一.[参考文献]11【CoukosG.RubinSC.Chemotherapyresistencelnovariancan.cer:newmolecularperspectiveslJjObstetandGynecol,1
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