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1、电刺激对脑梗死大鼠突触界面结构的影响69o0电刺激对脑梗死大鼠突触界面结构的影响何祥,冯荚中国临床康复第8卷第37期2004.11-05出版ChineseJournalofClinicalRehabilitation,November52004Vo1.8No.31?基础研究?何祥,冯葵,解放军沈阳军区总医院神经内科,辽宁省沈阳市llO0l6何祥,男,l945年生,黑龙江省兰西市人,汉族,1969年哈尔滨医科大学毕业,主任医师,硕士生导师,主要从事神经病,神经眼科学的研究.JC23896l02@l63.cam电话:+86.24.2305
2、273中图分类号:R743文献标识码:A文章编号:1671—5926(2004)31—6900—02收稿日期:2004—08—05修回日期:2004—09—08(04/SN)EffectofelectricstilnulationonthesynapticinterracestructureinratsfollowingcerebralinfarctionXiangHeYanFengXiangHeYanFengDepartmentofNeurology,ChinesePLAGeneralHospitalofShenyangMilita
3、ryAreaCommand,Shenyangl10016,LiaoningProvince,ChinaXiangHe,Male,HanNationality,Bornin1945inLanxiCity,HeilongjiangProvinee,China,GraduatedfromHarbinMedicalUnive~ityinl969,Chiefphysician,Master'stutor.Researchdirection:neuropathyandneulo.oph.tholmology.JC23896l02@l63.cam'
4、Telephone:+86—24—23056273Received:2004—08—05Accepted:20O4—09—08AbstractAⅡ:Toinvestigatetheinfluenceofdifferentkindsofelectricstimulationonthesynapticinterfacestructureinratsaftercerebralinfarction.METH0DS:FiftyhealthyadultWistarratswereselected.andonly300fthamweresucces
5、sfullymadeintothemodelsofmiddlecerebralarteryol2.clusionwiththeintraluminalmamentocclusion.Thentheyweredividedrandomlyintocontrolgroup,ipsilateralelectricstimulationgroupandbilat—eralelectricstimulationgroup.Thesynapticinterfacestructureandthechangesofitsindexesofratsaf
6、tercerebralinfarctionwereanalyzedwithtl'ansml$$1onelectronnncroscopyandcomputerlmageprocessingsystem.RESULTS:Comparedwiththecontrolgroup.thewidthofsynapticcleft【(25.84±3.49)nn1]wasnarrowedobviouslyintheipsilateralelectriestimu.1ationgroup(P<0.01),thethicknessofpostsy
7、napticdensity【(57.13±10.29)nn1]wasthickenedsignificantly(P<0.01),thelengthofsynapticactivezone【(314.36±24.92)nm]becameobviouslylonger(P<0.01),andthecurvatureofsynapticinterface【(1.145±0.160)lul1]hadnosignificantchanges(P>0.05).Inthebilateralelectricstimulationg
8、roup,thewidthofsynapticcleft[(21.9l±3.72)am]becamenarrower(P<0.01),thethicknessofpostsynapticdensity【(70.15
