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1、22例颅内静脉窦血栓形成临床研究【摘要】目的加深对脑静脉血栓形成的认识、提高诊疗水平。方法回顾性分析南方医科大学附属珠江医院22例脑静脉血栓形成病例的年龄、病因、临床症状、实验室及影像学资料、治疗方法。结果22例患者中，男：女比例1∶1；年龄自16岁到61岁；临床症状以头痛最为常见，可伴发呕吐、视乳头水肿、癫痫、肢体偏瘫、语言障碍、动眼神经麻痹等局灶性神经功能损害及意识障碍；影像学检查可采用MRV/DSA/CTV，血栓累及侧窦、上矢状窦最常见，且常合并累及多个静脉/静脉窦；经抗凝、降颅压、对症等治疗，有20例症状缓解，复查提示
2、原来血栓形成的静脉/静脉窦不同程度的再通；2例病情加重，其中1例死亡。结论颅内静脉窦血栓形成病因多种，发病形式多样，临床表现无特异性，随着磁共振MRV、CTA、DSA的应用，脑静脉血栓形成的诊断已不是难题，且治疗效果较好；另外神经介入治疗值得关注与期待。【关键词】颅内静脉窦血栓；分析；诊断及治疗22casesofintracranialvenoussinusthrombosisinclinicalanalysisHUANGHan-ning，XIEHui-fang，HUANGDan-dan，etal.GaozhouPeople’
3、sHospital，Gaozhou，525200，China14【Abstract】ObjectiveTodeepenunderstandingofcerebralvenousandsinusthrombosis,improveourdiagnosisandtherapy.MethodsAnalyzedthedatasof22patientsfromZhuiangAffilatedHospitalofSouthernMedicalUniversity,includedage,causes,clinicalsymptoms,th
4、edatasoflaboratoryandimaging,andtherapeuticregimen.ResultsMale-to-femaleratiowas1∶1,agingfrom16to61.Themostcommonsymptomwasheadache.Theconcomitantsymptomsincludedvomiting,papilloedema,epilepsy,paralysis,languagedisordersandsoon,whichwerefocalneurologicimpairment,ocu
5、lomotorparalysis,consciousnessdisorders.ImagingexamineincludeMRV,DSAandCTV.Themostcommonthrombosisisintransversesinusandsuperiorsagittalsinus,andofteninvolvedseveralvenousandsinus.Afterthetherapyofanticoagulation,decreasedintracranialpressureandsoon,20patientsacquir
6、edsymptomaticrelief,whoseimagingreviewshowedthevenousorsinushadvaryingdegreesofrecanalization.2patients’conditionsaggravated,oneofwhomwasdeadinthe14end.ConclusionCVSThasdifferentkindsofcausesandvarioustypesofonset.AndthereisnouniqueclinicalmanifestationforCVST.Along
7、withtheapplicationofMRV，CTAandDSA,thediagnosisofCVTisnotdifficult.Andwegetagoodtreatmenteffect.Inaddition,interventionalneuroradiologyshouldbepaidmoreattentionandbeworthexpecting.【Keywords】Cerebralvenousandsinusthrombosis;Analysis;Diagnosisandtherapy作者单位：525200广东省高州
8、市人民医院（黄汉宁黄丹丹）;南方医科大学附属珠江医院（谢惠芳颜振兴刘亚杰）颅内静脉窦血栓形成（cerebralvenousandsinusthrombosis,CVST）是由多种原因所致的脑静脉回流受阻的一组疾病，发病形式多样，临床表现无特异性，诊断较困难，容易漏诊误诊。为加
