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1、性传播疾病潜在血源传播患者梅毒血清学TRUST/TPPA与IgM抗体联合检测122341林丽蓉,但冰,付左根,杨波,潘锡涛,杨天赐[摘要]目的为潜在血源传播患者筛选梅毒血清学传染病指标。方法采用回顾性研究,对2006年6月1日~2009年12月31日本院23720例潜在血源传播患者与门诊患者的TRUST/TPPA联合检测结果进行分析比较;分析不同年度潜在血源传播患者TRUST/TPPA+的百分率变化;对其中118份TRUST/TPPA+的潜在血源传播患者血清标本同时采用TPPA法和FTAAB
2、S法进行TpIgM抗体检测。结果潜在血源传播患者和门诊患者的梅毒抗体阳性率分别为8.62%和26.69%,二者差异有显著性;在梅毒抗体阳性标本中,TRUST/TPPA+占有相当的比例,二者分别为3.12%和7.50%;潜在血源传播患者中TRUST/TPPA+的百分率呈逐年上升趋势;118份TRUST/TPPA+的潜在血源传播患者血清,经TPPA法和FTAABS法检出TPIgM抗体阳性分别为13例和10例。结论潜在血源传播患者的梅毒传染性指标的监测应至少包含特异性抗体试验,如TPPA;TPIg
3、M检测有助于判断其传染性。[关键词]梅毒血清学;潜在血源传播患者;梅毒螺旋体明胶凝集试验;梅毒甲苯胺红不加热血清反应素试验;梅毒IgM抗体[中图分类号]R759.1[文献标识码]A[文章编号]1001-7089(2010)05-0446-03SerologicalDetectionbyCombinationofTRUSTwithTPPAandIgMAntibodyforSyphilisPatientswithLatentBloodtransmittedRisk122341LINLir
4、ong,DANBing,FUZuogen,YANGBo,PANXitao,YANGTianci(1CenterofClinicalLaboratory,XiamenUniversityZhongshanHospital,Xiamen361004,China;2MedicalCollegeofXiamenUniversity,Xiamen361005,China;3XiamenConvalescentHospitalofArmedPolice,Xiamen361005,China;4Medica
5、lTechnologyCollegeofFujianMedicalUniversity,Fuzhou350004,China)[Correspondingauthor]YANGTianc,iEmai:lytc@xmu.edu.cn[Abstract]ObjectiveToselectserologicalscreeningindicatorsforsyphilispatientswithlatentbloodtransmittedrisk.MethodsAretrospectivestudyon
6、theTRUSTandTPPAcombinationdetectionmethodwasconductedbetweenpatientsatlatentbloodtransmittedriskandoutpatientsinourhospitalfrom,1June,2006to31December,2009.ThepercentofTRUST/TPPA+inpatientswithlatentbloodtransmittedriskwereanalyzedindifferentyears.TpI
7、gMantibodiesweredetectedin118casesofTRUST/TPPA+patientsatlatentbloodtransmittedrisk.ResultsSyphilisantibodypositiverate(26.69%)ofoutpatientswassignificantlyhigherthanpatientswithlatentbloodtransmittedrisk(8.62%).TherateofTRUST/TPPA+inthesyphilisposi
8、tivepatientswere7.50%and3.12%.ThepercentofTRUST/TPPA+inpatientswithlatentbloodtransmittedriskisgrowingsteadilyyearafteryear.13and10IgMantibodypositivespecimenswereseekedoutofthe118latentbloodtransm
