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1、免疫肠内营养支持对老年重症脑卒中患者营养状况和免疫功能的影响覃艳琼(华中科技大学同济医学院附属梨园医院老年病科,湖北武汉430070)【摘要】目的:探讨免疫肠内营养支持对老年重症脑卒中患者营养状况和免疫功能的影响。方法:选择我院收治的66例老年重症脑卒中患者,随机将其分为观察组和对照组各33例,观察组给予免疫肠内营养支持治疗,对照组给予常规院内营养支持治疗,对比两组患者在治疗前、治疗后第1及第2周时患者的营养状况和免疫功能指标的变化情况。结果:治疗第1周及第2周后,观察组IgG、IgM、IgA及CD4+、CD8+水平较同时间段的对照组为优,比
2、较差异有统计学意义(P<0.05),两组治疗第2周时IgG、IgM、IgA及CD4+、CD8+指标均显著优于治疗前,比较差异有统计学意义(P<0.05);观察组在治疗第1周及第2周时的TP、TC、TG及Hb水平较同时间段的对照组为优,比较差异有统计学意义(P<0.05),两组治疗第2周时TP、TC、TG及Hb指标均显著低于治疗前,比较差异有统计学意义(P<0.05)。结论:对于老年重症脑卒中患者而言,应用免疫肠内营养支持不仅可在一定程度上显著改善患者的营养状况,而且还能提高患者机体免疫力,值得临床推广应用。【关键词】重症脑卒中;老年人;营养状
3、况;免疫功能EffectofimmuneenteralnutritionsupportonnutritionalstatusandimmunefunctioninelderlypatientswithseverestrokeQINYan-qiong(DepartmentofGeriatrics,HuazhongUniversityofScience,TongjiMedicalCollegeofLiyuanHospital,HubeiWuhan430070,China)[Abstract]Objective:Toexploretheeffect
4、ofenteralnutritionsupportonnutritionalstatusandimmunefunctioninelderlypatientswithseverestroke.Methods:inourhospital66casesofelderlypatientswithseverestrokeweredividedintotheobservationgroupandthecontrolgroup,with33casesineachgroup.Thepatientsoftheobservationgroupweregivene
5、nteralimmunonutritionsupporttreatment,andthepatientsofthecontrolgroupweregivenroutinehospitalnutritionalsupporttreatmentandbeforetreatment,after1and2weekstreatmentnutritionalstatusandimmunefunctionchangescomparisonoftwogroupswerecompared.Results:after1weekand2weekstreatment
6、IgG,IgM,IgAandCD4+andCD8+oftheobservationgroupwerehigherthanthecontrolgroup,andthedifferencewasstatisticallysignificant(P<0.05),after2weekstreatmentIgG,IgM,IgAandCD4+,CD8+oftwogroupsweresignificantlysuperiortobeforetreatment,thedifferencewasstatisticallysignificant(P<0.05);
7、After1weekand2weekstreatmentTP,TC,TGandHblevelsoftheobservationgroupcomparedwiththecontrolgroup,andthedifferencewasstatisticallysignificant(P<0.05),after2weekstreatmentTP,TC,TGandHboftwogroupsweresignificantlylowerthanbeforetreatment,andthedifferencewasstatisticallysignific
8、ant(P<0.05).Conclusion:fortheelderlypatientswithseverestrokeandapplicationofimmune