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时间:2018-07-09
《卵巢癌浸润淋巴细胞的研究进展论文》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、卵巢癌浸润淋巴细胞的研究进展论文【关键词】卵巢癌肿瘤浸润淋巴细胞免疫逃逸卵巢癌是女性生殖器官常见的肿瘤之一,其术后长期生存率低,且复发率高[1]。提高患者的抗肿瘤免疫功能,对其病情的发展及预后有重要的临床应用价值。肿瘤浸润淋巴细胞(tumorinfiltratinglymphocyte,TIL)是最近受到国内外学者特别关注的一种新的免疫活性细胞,它具有高效、特异、副作用小等优点。然而,新鲜提取的TIL抗瘤活性十分低下[2],之后有研究表明恶性肿瘤患者的免疫系统在肿瘤局部和全身都处于耐受或缺陷状态[1.freeloralTcells,.freelmuno
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7、latoryTcellsinovariancarcinomafostersimmuneprivilegeandpredictsreducedsurvival[J].NatMed,2004,10:942949.[15]ElAndaloussiA,LesniakMS.AnincreaseinCD4+CD25+FOXP3+regulatoryTcellsintumorinfiltratinglymphocytesofhumanglioblastomamultiforme[J].NeuroOncol,2006,8:234243.
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