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1、Title:TheconundrumsurroundingtheuseofnaturalhealthproductsinprostatecancerpatientcareAuthors:JenniferA.Locke1,2andEmmaS.TomlinsonGuns21FacultyofMedicine,UniversityofToronto,1King'sCollegeCircle,Toronto,ON2DepartmentofUrologicSciences,UniversityofBritishColumbia,TheProstateCentreatVancouverGene
2、ralHospital,2660OakStreet,Vancouver,BCCorrespondingauthor:jennifer.locke@utoronto.caIntroductionSeveralquestionsarisewhendebatingtheuseofnaturalhealthproducts(NHPs)inprostatecancertreatmentregimes:WhatareNHPs?Howdophysiciansandpatientsperceivethem?Whattherapeuticroledotheyplayinthecareofprosta
3、tecancerpatients?WhataresomeoftheissuessurroundingNHPs?MostimportantlyforthoseprostatecancerpatientswhowanttotakeNHPs,howcanphysiciansandregulatorybodiesassistintheirdecisionsaswellastheimplementationofNHPsintotreatmentregimesinasafeandefficaciousmanner?Thisarticleaddressesmanyofthesepressingq
4、uestions.NaturalHealthProductsdefinedHealthCanada’sNaturalHealthProductsDirectoratedefinesanaturalhealthproduct(NHP)asanyofthefollowing:vitaminsandminerals,herbalremedies,homeopathicmedicines,traditionalmedicinessuchastraditionalChinesemedicines,probioticsandotherproductssuchasaminoacidsandess
5、entialfattyacids1.PerceptionsofNHPsAsonewouldexpectwiththeterm“naturalhealthproducts”manypatientsviewthemasboth“natural”and“healthy”andoftenassumetheyaresafe.Fiftytofifty-twopercentofhealthyadultsintheUnitedStatestakeNHPsonaregularbasisandthedistributionofuse10amongthispopulationisdependentons
6、everalfactorsincludinggender,age,dietaryhabits,educationlevelandphysicalactivity2,3.ProstatecancerpatientshavebeenstudiedasapopulationregardingtheirNHPintakeandhaveagreaterthanaveragehistoryofsupplementuse4.Intheprostatecancerpreventiontrialwhichwaswidelyreportedonin2008,85%ofpatientspoledregu
7、larlyconsumedatleastoneNHP5whileinCanadaandtheUS58%and74%ofallcancerpatients,respectively,reporteduseofNHPs2,6.Ontheotherhand,theendorsementofNHPuseamongprostatecancerpatientsfromthephysicians’perspectiveremainscontroversial.Eighty-twoa
