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时间:2020-05-14
《金华市不同人群麻疹抗体水平及免疫策略研究.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·8·浙江预防医学2011年第23卷第7期ZhejiangPreventiveMedicine,.20垫—!金华市不同人群麻疹抗体水平及免疫策略研究王凤英吴晓虹陈志清【摘要】目的了解金华市本地人群与外来流动人口麻疹抗体水平,为制定和完善麻疹免疫策略提供科学依据。方法选取7个年龄组的630名本地人口和210名流动人口、180名18~25岁育龄期妇女、180名孕妇和9O名8月龄以下儿童母亲,共1290人开展麻疹抗体水平监测,根据监测结果提出免疫策略。结果本地人群的麻疹抗体阳性率、保护率和几何平均浓度(GMC)分别为92.54%、78.73%和1774.19mlU/ml;外来流动人
2、I=I的麻疹抗体阳性率、保护率和几何平均浓度(GMC)分别为66.67%、4o.95%和269.90mlU/ml,本地人群的阳性率、保护率和GMC均明显高于外来流动人口(尸<0.O1)。育龄期妇女麻疹抗体阳性率、保护率和GMC分别为93.33%、62.78%和1194.13mlU/ml;孕妇麻疹抗体阳性率、保护率和GMC分别为94.44%、65.56%和1298.82mlU/ml;8月龄以下未患病儿童母亲的抗体GMC明显高于患病儿童母亲(P<0.05),4类特殊人群的疫苗接种率和接种意识均低于50%。结论金华市本地人群麻疹免疫水平较高,4类特殊人群的麻疹疫苗接种率、接种意识和
3、免疫水平均不高。应加强常规免疫、强化免疫、应急接种、规范接种和健康教育等。【关键词】麻疹;不同人群;抗体监测;免疫策略中图分类号:R186;R511.I文献标识码:A文章编号:1007—0931(2011)07—0008—04StudyonMeaslesImmunityLevelinDiferentPopulationsandtheImmunizationStrategyofJinhuaCityWANGFeng—yg,WUXiao—hong,CHENZhi—qing.TheCenterforDiseaseControlandPreventionofJinhuaCity,Jin
4、hua,Zhejiang321002,China.【Abstract】ObjectiveToknowthemeaslesimmunityleveloflocalpeopleandmigrantpopulationinJinhuacity,providingascientificbasisforthestrategyofmeas]~immunization.MethodsAtotalof1290peopleweresdectedtodetectthemealiesantibodylevel,including630localpeople,210migrantpopulation
5、,180child—bearingwomenaged18—25yearsold,180pregnantwomenand90mothersofchildrenunder8months.Immunizationstrategywouldbeputforwardaccordingtothesurveillanceresults.ResultsThemeaslesantibodypositiverate,theprotectiverateandtheGeometricMeanConcentration(GMC)oflocalpopulationwere92.54%,78.73%and
6、1774.19mlU/mlrespectively,whichweresignificantlyhisherthanthemigrantpopulationwith66.67%,40.95%and269.90mlU/mlrespectively(P<0.01).Theantibodypositiverate,theprotectiverateandGMCofchild—bearingwomenwere93.33%,62.78%and1194.13mlU/ndrespectively,andthepregnantwomenwere94.44%65.56%and1298.82ml
7、U/mlrespectively.Amongthechildren,undereightmonthstheGMCofsickchildren’smotherswassignificantlylowerthanthatofnon—sickchildren’smothers(P<0.05),Boththevaccineimmunizationrateandvaccinationconsciousnessofthosefourspecialgroupswerebelow50%CondnsionThemeasl
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