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《预注阿曲库铵对不同剂量顺式阿曲库铵时效的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、西南军医2013年3月第15卷第2期JournalofMilitarySurgeoninSouthwestChina,Vo1.15,No.2,Mar.,2013·129·预注阿曲库铵对不同剂量顺式阿曲库铵时效的影响廖常莉,周述之,赵晓蓉,姜鲜[摘要]目的观察预注小剂量阿曲库铵对不同ED顺式阿曲库铵时效的影响。方法将80例ASAI.II级手术患者随机分为四组(n=20):A组3ED(0.15mg/kg)顺式阿曲库铵、B组4ED(0.2mg/kg)顺式阿曲库铵、C组预注射0.1mg/kg阿曲库铵,复合3ED顺式阿曲库铵、D组预注射0.1m
2、g/kg阿曲库铵,复合4ED顺式阿曲库铵。观察各组顺式阿曲库铵起效时间、临床有效作用时间、术毕恢复时间;评估气管插管条件及不良反应。结果B组与A组相比,B组顺式阿曲库铵起效时间无明显差异(P>0.05),而C、D两组起效时间较A、B组明显缩短(P<0.05),D组更短(尸3、0.1mg&g)阿曲库铵复合4ED顺式阿曲库铵,肌松起效时间短,临床有效作用时间长,术毕恢复快,气管插管条件满意,不良反应少,适合,I缶床推广。[关键词]阿曲库铵;ED;顺式阿曲库铵;时效[中图分类号]R971.2[文献标识码]A[文章编号]1672—7193(2013)02—0129.03Doi:10.3969/j.issn.1672—7193.2013.02.004IeAfectionofPre—injectionofAtracuriumontheAgeofCisatracuriumofDiferentDosagesLiaoCha4、ngli,ZhouShuzhi,ZhaoXiaorong,JiangXian,DepartmentofAenesthesis,theAfiliatedHospitaltoLuzhouMedicalCollege,LuzhouCity,SichuanProvince,646000,RR.ChinaABSTRACTObjectiveToobservetheafectionofpre—injectionofatracuriuminsmalldosageontheageofED95ofcisatracuriumofdiferentdosage5、s.Methods80casesofASAIIIforsurgerywererandomlydividedinto4groups.20casesineach:GroupAwith3ED95ofcisatracurium(0.15mg/kg),GroupBwith4ED95ofcisatracurium(O.2mg/kg),GroupCwithpre-injectionofatracurium(0.1mg/kg)plus3ED95ofcisatracuriumandGroupDwithpre—injectionofa~acurium(O6、.1mg/kg)plus4ED95ofcisatracurium;anobservationwasmadetotheonsettime,theefectivedurationandthetimeforrecoveryafteroperationineachgroupandthe~achealintubationcon—ditionandside-efectswereestimated.Re~u/teThereexistednoobviousdiferenceintheonsettimeofatracuriumbetweenGroupA7、andGroupB(P<0.05)whiletheonsettimeofGroupCandofGroupDwasshorterthanthoseofGroupAandGroupB(P<0.05),theonsettimeofGroupDwastheshortest(0.05):theefectivedurationofGroupBandofGroupDwaslongerthanthoseofGroupAandGroupD(P<0.O5),theefectivedurationofGroupDwasthelongest(P<0.O5);8、thetimeforrecoveryafteroperationinGroupBandinGroupDwasobviouslylongerthanthoseinGroupAandGroupC(P<0.05)anditto
3、0.1mg&g)阿曲库铵复合4ED顺式阿曲库铵,肌松起效时间短,临床有效作用时间长,术毕恢复快,气管插管条件满意,不良反应少,适合,I缶床推广。[关键词]阿曲库铵;ED;顺式阿曲库铵;时效[中图分类号]R971.2[文献标识码]A[文章编号]1672—7193(2013)02—0129.03Doi:10.3969/j.issn.1672—7193.2013.02.004IeAfectionofPre—injectionofAtracuriumontheAgeofCisatracuriumofDiferentDosagesLiaoCha
4、ngli,ZhouShuzhi,ZhaoXiaorong,JiangXian,DepartmentofAenesthesis,theAfiliatedHospitaltoLuzhouMedicalCollege,LuzhouCity,SichuanProvince,646000,RR.ChinaABSTRACTObjectiveToobservetheafectionofpre—injectionofatracuriuminsmalldosageontheageofED95ofcisatracuriumofdiferentdosage
5、s.Methods80casesofASAIIIforsurgerywererandomlydividedinto4groups.20casesineach:GroupAwith3ED95ofcisatracurium(0.15mg/kg),GroupBwith4ED95ofcisatracurium(O.2mg/kg),GroupCwithpre-injectionofatracurium(0.1mg/kg)plus3ED95ofcisatracuriumandGroupDwithpre—injectionofa~acurium(O
6、.1mg/kg)plus4ED95ofcisatracurium;anobservationwasmadetotheonsettime,theefectivedurationandthetimeforrecoveryafteroperationineachgroupandthe~achealintubationcon—ditionandside-efectswereestimated.Re~u/teThereexistednoobviousdiferenceintheonsettimeofatracuriumbetweenGroupA
7、andGroupB(P<0.05)whiletheonsettimeofGroupCandofGroupDwasshorterthanthoseofGroupAandGroupB(P<0.05),theonsettimeofGroupDwastheshortest(0.05):theefectivedurationofGroupBandofGroupDwaslongerthanthoseofGroupAandGroupD(P<0.O5),theefectivedurationofGroupDwasthelongest(P<0.O5);
8、thetimeforrecoveryafteroperationinGroupBandinGroupDwasobviouslylongerthanthoseinGroupAandGroupC(P<0.05)anditto
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