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1、对比分析短效与长效硝苯地平治疗妊娠高血压的临床效果杨海燕(四川省达州市妇幼保健院药剂科四川达州635000)【摘要】目的:评析对比短效与长效硝苯地平治疗妊娠高血压的临床效果。方法:现从我院诊疗的妊娠高血压患者中筛选出98例,依据随机分配原则将其分为对照组与研究组(49例),分别采用短效硝苯地平、长效硝苯地平治疗,完成为期lw的治疗后观察患者的血压变化情况,同时观察产妇分娩方式及母婴结局等的差异。结果:对比两组患者治疗前SBP、DBP无明显差异(P>0.05),对比各组治疗前后血压均得以降低(P<0.05),相比下研究组的血压控制效果更为确切(PV0.05);研究组的自然分娩率明显
2、高于对照组(PV0.05),而从母婴结局看,产妇胎盘早剥、产后出血、胎儿宫内窘迫及死亡等的发生率与对照组相比均明显更低(PV0.05)。结论:针对妊娠高血压给予长效硝苯地平治疗降压效果更为显著,H有助于减少母婴不良结局的发牛,推荐作为临床治疗的首选药物。【关键词】短效;长效;硝苯地平;妊娠高血压【中图分类号】R544.1【文献标识码】A【文章编号】2095-1752(2016)22-0043-02TocomparetheclinicaleffectofshortactingandIong-actingnifedipineinthetreatmentofpregnancyinduc
3、edhypertensionYangHaiyan.MaternalandChildHealthCareHospitalofDazhouCity,SichuanProvince,Dazhou635000,China[Abstract]ObjectiveAcomparativestudyofclinicaleffectofshortactingandIong-actingnifedipinetreatmentofhypertensioninpregnancy.MethodsFromourhospitaldiagnosisandtreatmentofpatientswithpregna
4、ncyinducedhypertensionscreened98cases,accordingtotheprincipleofrandomassignmentwillbetheascontrolgroupandthestudygroup(49cases),respectively,usingshortactingnifedipineandnifedipinetreatment,observationofbloodpressurechangeinpatientsafterthecompletionoftheperiodof1Wtreatment,andtoobservethedif
5、ferencesinmaternalmodeofdeliveryandmaternalandneonataloutcomes.ResultsTreatmentofSBRDBP,nosignificantdifferenee(P>0.05)werecomparedbetweenthetwogroupsofpatients,bloodpressurecomparedbeforeandaftertreatmentineachgroupwereabletodecreased(P<0.05),thebloodpressureinstudygroupcomparedtotheco
6、ntroleffectismoreprecise(P<0.05);studygroupofnaturalbirthratewassignificantlyhigherthanthecontrolgroup(P<0.05),andfromthematernalandneonataloutcomes,maternalplacentalabruption,postpartumhemorrhage,fetaldistressanddeathincideneeandcontrolgroupcomparedweresign讦icantlylower(P<0.05).Conc
7、lusionThepregnancyinducedhypertensiontreatedwithIong-actingnifedipinetreatmentforantihypertensiveeffectismoresignificant,andcontributetotoreducetheoccurreneeofadversematernaloutcomes,recommendedasthedrugofchoiceforclinicaltreatment・【Keywords]