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时间:2020-04-17
《不同剂量阿司匹林肠溶片治疗急性脑梗死的疗效观察.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、临春医学工程2014年9月第21卷第9期·1143··论著·(·临床研究)不同剂量阿司匹林肠溶片治疗急性脑梗死的疗效观察栾伟星(山东省泰安市第一人民医院,山东泰安276000)【摘要】目的研究不同剂量阿司匹林肠溶片治疗急性脑梗死的l临床疗效。方法选取2013年2月到2014年3月我院收治的急性脑梗死患者90例,随机分为两组各45例,两组患者均给予低分子肝素。其中A组给予100m#d阿司匹林肠溶片进行治疗,B组给予300mg/d阿司匹林肠溶片进行治疗,比较两组·临床疗效以及治疗前、后患者神经功能缺损评分。结果B组总有效率93
2、.3%(42/45)显著高于A组的73.3%(33/45),两组比较差异具有统计学意义(P<0.O5);两组治疗后神经功能缺损评分均显著优于治疗前,与治疗前比较差异具有统计学意义(P3、.1143EficacyofDiferentDosesofAspirinEnteric—CoatedTabletsintheTreatmentofAcuteCerebralInfarctionLUANWeixingr孔伽FirstPeopleHospital,Taian276000,China)[Abstract]ObjectiveTostudytheclinicaleficacyofdiferentdosesofenteric—coatedaspirintabletsinthetreatmentofacutecerebr4、alinfarction.Methods90patientswithacutecerebralinfarctioninourhospitalfromFebruary2013toMarch2014wereselectedandrandomlydividedintotaogroups,with45casesineachgroup.Allcaseweretreatedwithlowmolecularweightheparin,inaddition,patientsingro,pAweregiven100mg/dofaspirin5、enteric—coatedtabletsfortreatment,whilepatientsingroupBweregiven300mg/dofasp~inenteric—coatedtabletsfortreatment.Theclinicalefectsandneurologicaldeficitscoresbeforeandaftertreatmentwerecomparedbetweentwogroups.ResultsThetotaleffectiverateofgroupBwas93-3%(42/45),si6、gnificantlyhigherthan73.3%(33/45)ofgroupA(尸<0.05).Theneurologicaldeficitscoresincreasedsignificantlyinbothgroupaftertreatment(P<0.05),andtheneurologicaldeficitscoreaftertreatmentofgroupBwassignificantlybetterthanthatofgroupA(P7、teric—coatedaspirintabletsinthetreatmentofacutecerebralinfarctionhasgoodclinicaleficacy,andcansignificantlyimprovepatients’neurologicalfunction.【Keywords】Enteric—coatedaspirintablets;Acutecerebralinfarction;Eficacy;Diferentdoses脑梗死是指局部的脑组织血液循环障碍,导致缺氧和缺血颅脑CT或者MRI检查8、确诊。在患者知情同意下将患者随机分的发生,进而发生脑软化坏死。该病的主要原因为脑部动脉出为A组和B组:A组45例,男性24例,女性21例,年龄介现粥样硬化或血栓形成,引起管腔狭窄,甚至是闭塞,最终导于45~80岁,平均年龄为(58-3±1.5)岁;B组45例,男性致局灶性的脑供血不足而发病[1-31。抗
3、.1143EficacyofDiferentDosesofAspirinEnteric—CoatedTabletsintheTreatmentofAcuteCerebralInfarctionLUANWeixingr孔伽FirstPeopleHospital,Taian276000,China)[Abstract]ObjectiveTostudytheclinicaleficacyofdiferentdosesofenteric—coatedaspirintabletsinthetreatmentofacutecerebr
4、alinfarction.Methods90patientswithacutecerebralinfarctioninourhospitalfromFebruary2013toMarch2014wereselectedandrandomlydividedintotaogroups,with45casesineachgroup.Allcaseweretreatedwithlowmolecularweightheparin,inaddition,patientsingro,pAweregiven100mg/dofaspirin
5、enteric—coatedtabletsfortreatment,whilepatientsingroupBweregiven300mg/dofasp~inenteric—coatedtabletsfortreatment.Theclinicalefectsandneurologicaldeficitscoresbeforeandaftertreatmentwerecomparedbetweentwogroups.ResultsThetotaleffectiverateofgroupBwas93-3%(42/45),si
6、gnificantlyhigherthan73.3%(33/45)ofgroupA(尸<0.05).Theneurologicaldeficitscoresincreasedsignificantlyinbothgroupaftertreatment(P<0.05),andtheneurologicaldeficitscoreaftertreatmentofgroupBwassignificantlybetterthanthatofgroupA(P7、teric—coatedaspirintabletsinthetreatmentofacutecerebralinfarctionhasgoodclinicaleficacy,andcansignificantlyimprovepatients’neurologicalfunction.【Keywords】Enteric—coatedaspirintablets;Acutecerebralinfarction;Eficacy;Diferentdoses脑梗死是指局部的脑组织血液循环障碍,导致缺氧和缺血颅脑CT或者MRI检查8、确诊。在患者知情同意下将患者随机分的发生,进而发生脑软化坏死。该病的主要原因为脑部动脉出为A组和B组:A组45例,男性24例,女性21例,年龄介现粥样硬化或血栓形成,引起管腔狭窄,甚至是闭塞,最终导于45~80岁,平均年龄为(58-3±1.5)岁;B组45例,男性致局灶性的脑供血不足而发病[1-31。抗
7、teric—coatedaspirintabletsinthetreatmentofacutecerebralinfarctionhasgoodclinicaleficacy,andcansignificantlyimprovepatients’neurologicalfunction.【Keywords】Enteric—coatedaspirintablets;Acutecerebralinfarction;Eficacy;Diferentdoses脑梗死是指局部的脑组织血液循环障碍,导致缺氧和缺血颅脑CT或者MRI检查
8、确诊。在患者知情同意下将患者随机分的发生,进而发生脑软化坏死。该病的主要原因为脑部动脉出为A组和B组:A组45例,男性24例,女性21例,年龄介现粥样硬化或血栓形成,引起管腔狭窄,甚至是闭塞,最终导于45~80岁,平均年龄为(58-3±1.5)岁;B组45例,男性致局灶性的脑供血不足而发病[1-31。抗
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