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时间:2020-02-29
《四妙消痹汤对类风湿关节炎活动期患者血小板参数和P-选择素的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、74陕西中医2017年1月第38卷第1期四妙消痹汤对类风湿关节炎活动期患者血小板参数和P-选择素的影响李琦,罗悦琼,陈孝强四川省简阳市中医医院(简阳641400)摘要目的:探究四妙消痹汤对类风湿关节炎活动期患者血小板参数和P-选择素的影响。方法:选取本院收治的类风湿关节炎患者63例,按照随机数表法分为观察组32例和对照组31例,分别给予四妙消痹汤、甲氨蝶呤治疗12周,比较治疗前后血小板参数和P-选择素、疗效、主要症状体征的积分。结果:治疗后观察组血小板参数PLT、MPV、PCT、PDW、Ps均下降,且观察组低于对照组,差异有统计学意义(P<0.05);观察
2、组总有效率高于对照组(P<0.05);治疗后两组的关节肿胀、关节疼痛、按压疼痛、晨僵时间积分均降低,且观察组低于对照组(P<0.05)。结论:四妙消痹汤可降低类风湿关节炎活动期患者血小板参数和P-选择素,在治疗类风湿关节炎方面有很好的疗效。主题词关节炎,类风湿/中西医结合疗法清热解毒剂/治疗应用@四妙消痹汤中图分类号:R593.22文献标识码:ADOI:10.3969/j.issn.1000-7369.2017.01.037EffectofSimiaoXiaobidecoctiononplateletparametersandP-selectelement
3、inpatientswithrheumatoidarthritisduringrheumatoidarthritisactivityLiQi,LuoYueqiong,ChenXiaoqiang.JianyangChineseMedicineHospitalinSichuanprovince(Jianyang641400)AbstractObjective:ToexploretheeffectofSimiaoXiaobidecoctiononplateletparametersandP-selectele-mentinpatientswithrheumato
4、idarthritisduringrheumatoidarthritisactivity.Methods:63caseswithrheumatoidarthritisinourhospitalwereselectedtoberandomlydividedintoobservationgroup32casesandthecontrolgroup31cases.Theobservationgroup’patientsweregiventoSimiaoXiaobidecoction,andthecontrolgroup’patientsweregiventome
5、thotrexate.Theplateletparametersbeforeandaftertreatment,therapeuticeffect,integralofmainsymp-tomsandsignswerecompared.Results:Aftertreatment,theobservationgroupPLT,MPV,plateletparametersPCT,PDWandPsweredecreased,andtheobservationgroupthaninthecontrolgroup,thedifferencewasstatisti-
6、callysignificant(P<0.05);thetotalefficiencyoftheobservationgroupwashigherthanthatofcontrolgroup(P<0.05);thetwogroupsaftertreatmentofjointswelling,jointpain,pressingpain,morningstiffnesstimepointswerelower,andtheobservationgroupthanthecontrolgroup(P<0.05).Conclusion:SimiaoXiaobidec
7、octioncanreducetplateletparametersandP-selectelementinpatientswithrheumatoidarthritis,thetreatmentofrheumatoidarthritishasagoodeffect.KeywordsArthritis,rheumatoid/integratedChinesetraditionalandwesternmedicinetherapyAntipyret-ic-Detoxicateagents/Therapeuticuses@SimiaoXiaobidecocti
8、on类风湿关节炎(Rheumatoidarthritis,RA)是
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