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时间:2019-05-15
《脑电双频谱指数和听觉诱发电位指数监测老年人地氟醚麻醉深度的评价》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据中华老年医学杂志2006年12月第25卷第12期ChinJGeriatr,December2006,V01.25,No.12脑电双频谱指数和听觉诱发电位指数监测老年人地氟醚麻醉深度的评价蔡进郭曲练唐朝辉891·临床研究·【摘要】目的探讨脑电双频谱指数(BIS)和听觉诱发电位指数(AEPindex)监测老年人地氟醚麻醉深度的可行性与有效性。方法选择听力正常拟行气管插管全麻患者60例,按年龄分为老年组和非老年组,每组30例。气管插管后吸入地氟醚维持麻醉,调整地氟醚呼气末浓度依次维持在0.6、1.0
2、最低肺泡有效浓度(MAC)和1.3MAC,每一浓度均稳定20min。记录各时点的BIS、AEPindex、平均动脉压(MAP)和心率的变化。结果老年组和非老年组T,期BIS分别为94.1±6.5和94.5±4.6,AEPindex分别为87.2±11.7和89.2±6.9,差异均无统计学意义。两组各时点地氟醚麻醉期(Ts、T。、Ts)BIS或AEPindex比麻醉前(T。)明显下降(P3、计学意义。两组BIS与地氟醚呼气末浓度呈显著负相关(Po.05)。非老年组在地氟醚各呼气末浓度时的AEPindex逐渐下降(P>o.05),在同一地氟醚呼气末浓度时,老年组AEPindex均明显低于非老年组(P4、浓度呈一定的剂量相关性,可用于监测老年人地氟醚麻醉深度,AEPindex可在一定程度上反映相同地氟醚呼气末浓度下老年人与非老年人麻醉深度的差异。【关键词】诱发电位,听觉;脑电描记术;麻醉,吸人;甲醚类Evaluationofbispectralindexandauditory-evokedpotentialsindexformonitoringthedepthofdesfluraneanesthesiaintheelderlyCAfJin,GUOQu—lian,了、ANGZhao—hui.Depart5、mentofA佗8s旃esioZDgy,XiangyaHospital,CentralSouthUniversity,Changsha410008,C矗ina[Abstract]0bjectiveToinvestigatetheeffectivityofbispectralindex(BIS)andauditory—evokedpotentialsindex(AEPindex)inmonitoringthedepthofdesfluraneanesthesiaintheelderly.MethodsS6、ixtypatients(ASAgradeI~m)withoutobviousauditoryandpsychiatricdysfunctionundergoinggeneralanesthesia。wereenrolledinthisstudy,andtheyweredevidedintotheelderlygroup(n一30)andthenon-elderlygroup(n=30)accordingtotheage.Aftertheendotrachealintubation,the1ungsw7、ereventilatedwithdesfluraneinoxygen;End-tidalconcentrationsofdesfluraneweremaintainedat0.6,1.0minimumalveolarconcentrations(MAC)and1.3MACfor20minutes,respectively.ThechangesofBIS,AEPindex,meanarterialbloodpressure(MAP)andheartrate(HR)wererecordedsimulta8、neously.ResultsIntheelderlyandnon-elderlygroups,BISwere94.1±6.5and94.5±4.6(P>O.05),andAEPindexatpre-anesthesiawere87.2±11.7and89.2±6.9(P>0.05)respectively,whichshowednostatisticdifferencebetweentWOgroups.BISandAEPindexdecreasedsi
3、计学意义。两组BIS与地氟醚呼气末浓度呈显著负相关(Po.05)。非老年组在地氟醚各呼气末浓度时的AEPindex逐渐下降(P>o.05),在同一地氟醚呼气末浓度时,老年组AEPindex均明显低于非老年组(P4、浓度呈一定的剂量相关性,可用于监测老年人地氟醚麻醉深度,AEPindex可在一定程度上反映相同地氟醚呼气末浓度下老年人与非老年人麻醉深度的差异。【关键词】诱发电位,听觉;脑电描记术;麻醉,吸人;甲醚类Evaluationofbispectralindexandauditory-evokedpotentialsindexformonitoringthedepthofdesfluraneanesthesiaintheelderlyCAfJin,GUOQu—lian,了、ANGZhao—hui.Depart5、mentofA佗8s旃esioZDgy,XiangyaHospital,CentralSouthUniversity,Changsha410008,C矗ina[Abstract]0bjectiveToinvestigatetheeffectivityofbispectralindex(BIS)andauditory—evokedpotentialsindex(AEPindex)inmonitoringthedepthofdesfluraneanesthesiaintheelderly.MethodsS6、ixtypatients(ASAgradeI~m)withoutobviousauditoryandpsychiatricdysfunctionundergoinggeneralanesthesia。wereenrolledinthisstudy,andtheyweredevidedintotheelderlygroup(n一30)andthenon-elderlygroup(n=30)accordingtotheage.Aftertheendotrachealintubation,the1ungsw7、ereventilatedwithdesfluraneinoxygen;End-tidalconcentrationsofdesfluraneweremaintainedat0.6,1.0minimumalveolarconcentrations(MAC)and1.3MACfor20minutes,respectively.ThechangesofBIS,AEPindex,meanarterialbloodpressure(MAP)andheartrate(HR)wererecordedsimulta8、neously.ResultsIntheelderlyandnon-elderlygroups,BISwere94.1±6.5and94.5±4.6(P>O.05),andAEPindexatpre-anesthesiawere87.2±11.7and89.2±6.9(P>0.05)respectively,whichshowednostatisticdifferencebetweentWOgroups.BISandAEPindexdecreasedsi
4、浓度呈一定的剂量相关性,可用于监测老年人地氟醚麻醉深度,AEPindex可在一定程度上反映相同地氟醚呼气末浓度下老年人与非老年人麻醉深度的差异。【关键词】诱发电位,听觉;脑电描记术;麻醉,吸人;甲醚类Evaluationofbispectralindexandauditory-evokedpotentialsindexformonitoringthedepthofdesfluraneanesthesiaintheelderlyCAfJin,GUOQu—lian,了、ANGZhao—hui.Depart
5、mentofA佗8s旃esioZDgy,XiangyaHospital,CentralSouthUniversity,Changsha410008,C矗ina[Abstract]0bjectiveToinvestigatetheeffectivityofbispectralindex(BIS)andauditory—evokedpotentialsindex(AEPindex)inmonitoringthedepthofdesfluraneanesthesiaintheelderly.MethodsS
6、ixtypatients(ASAgradeI~m)withoutobviousauditoryandpsychiatricdysfunctionundergoinggeneralanesthesia。wereenrolledinthisstudy,andtheyweredevidedintotheelderlygroup(n一30)andthenon-elderlygroup(n=30)accordingtotheage.Aftertheendotrachealintubation,the1ungsw
7、ereventilatedwithdesfluraneinoxygen;End-tidalconcentrationsofdesfluraneweremaintainedat0.6,1.0minimumalveolarconcentrations(MAC)and1.3MACfor20minutes,respectively.ThechangesofBIS,AEPindex,meanarterialbloodpressure(MAP)andheartrate(HR)wererecordedsimulta
8、neously.ResultsIntheelderlyandnon-elderlygroups,BISwere94.1±6.5and94.5±4.6(P>O.05),andAEPindexatpre-anesthesiawere87.2±11.7and89.2±6.9(P>0.05)respectively,whichshowednostatisticdifferencebetweentWOgroups.BISandAEPindexdecreasedsi
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