低剂量超微分割和常规分割放疗对脑胶质瘤细胞的生物学效应比较

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1、英文缩写ATMBDDMEMDMSOdsDNADSBEBEDTAFBSFCMFITCGvHRSODPAGEPBSPSrpmTris“g英文全称英文缩写词一览表Ataxia—telangiectasiamutatedBasedamageDulbecco’SModifiedEagleMediumDimethylsulfcIxideDouble—strandedDNADoublestrandbreaksEthidiumbromideEthylenediaminetetraaceticacidFetalbovineserumFlowcytometricassayFluoresc

2、einisothiocyanateGrayHyper—radiosensitivityOpticaldensityPolyacrylamidegelelectrophoresisPhosphatebufferedsalinephosphotidylserineRotationperminuteTrihydroxymethylaminomethaneMicrogram中文全称共济失调毛细血管扩张突变碱基损伤Dulbecco改良细胞培养液二甲基亚砜双链DNA双链断裂溴化乙锭四乙酸二氨基乙烯胎牛血清流式细胞术异硫氰酸荧光素戈瑞低剂量辐射超敏感性光密度聚丙烯酰胺凝胶电泳磷酸盐

3、缓冲液磷脂酰丝氨酸姨

4、分三羟甲基氨基甲烷微克ComparisionofbiologicaleffectsbetweenuItra．MicrofractionatedradiotherapyandconventionalBackgroundRadiotherapyongliomacellsAbstractGliomaisthemostcommonmalignanttumorincentralnervoussystem，whichisfrom40to60percentinintracranialtumoul：Throughtheoperation，radiotherapy

5、，chemotherapyandmoleculartargetedtherapy,Themediansurvivalforthepatientswas14monthsandtheprognosisispoor．Radiotherapyisanimportanttreatmentforadjuncttherapyaftersurgeryandpatientwhoareinoperable．Inordertoprotectbrainorganization，tolerancedosemustbelimited．Sotheefficacyofadjuncttherapyaf

6、tersurgeryisnotsignificant，recurrenceandlocalinvasiona1．ealwaysoutofcontr01．Thestudyshowedthatmultipletumorcellshaveultra—microfractionatedallergicphenomenon．Sotar,weadoptultra—microfractionatedradiotherapytechnologywhichbasedonultra—microfractionatedallergicreactionandSLDR．Thismethodis

7、todivideconventionalfractionationintoequalandincaregulars．．jetintervalObjectiveTheaimofthisstudyistoexplorethewayofradiotherapythroughcomparingtheeffectofultra—microfractionatedradiotherapyandconventionalfractionationradiotherapvonGI，261111j_ceneMethods1DividedGL261cellsinlogarithmicgro

8、wthphaseintoCOntr01group,ultra—microfractionatedradiotherapygroupandconventionalradiotherapygroup,with3bottlescellseachgroup，radiatedfor3days．Exposedultra—microfractionatedgroupto0．6Gy,0．2Gyevery3min；exposedconventionalgroupto0．6Gyonetime，inthefirst3davsafterthestartofradiation