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时间:2019-02-24
《哮喘儿童血清白介素水平的循证评价》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、维普资讯http://www.cqvip.com31卷第1O期JiangsuMedJ,October2005,Vol31,No.10论著哮喘儿童血清白介素水平的循证评价徐美玉季健玲【摘要】目的评价儿童哮喘患者血清中II『4、IL-6、IL-8检测指标的意义。方法通过中国生物医学文献数据库(CBMdisc)、中文全文数据库全面检索国内已发表的文献,选择中国儿童哮喘患者与对照组血II.-4、IL-6、II.-8水平检测,由2位评价者按照上述检索策略收集文献,进行Meta分析。结果儿童哮喘患者发作期、缓解期血清中II,4分别较对照组上升89.99ng/L(95CI47.13~132.84)、25.
2、82ng/L(95CI15.78~35.86)(P3、medicineofresearchontheseruminterleukinsinchildrenwithasthmaXUMeiyu,JIJianling.DepartmentofPediatrics,AffiliatedHospital,NantongUniversity,Nantong226001,CHlNA[AbstractlObjectiveToevaluatethesignificanceofinterleukin(IL)一4,II一6andIL-8measure—mentsinchildrenwithasthm&MethodTheanalysisofallrelatedlite4、raturesinCBMdiscandChinesefulltextdatabasehasbeenmade.SelectioncriteriaweretheexaminationsofserumIL,4。IL一6andIL-8inChinesechildrenwithasthmaandcontro1groups.Aquantitativemeta—analysiswascarriedOUtbytworeviewsusingupdateinformationbasedoninclusionandexclusioncriteriafromthepapersavaila~ble.ResultsTh5、econcentrationsofIL-4duringattackphaseandcatabaticphaseinthepatientsweresignificantlyhigherthanthoseinthehealthysubjects,whichwereincreasdby89.99ng/I(95CI47.13~132.84)and25.82ng/I(95CI15.78~35.86)(P6、1)and183.15ng/1(95C1104.58~261.72),whichwerehigherthanthoseinthehealthysubjects(P7、andIL-8playaroleinthepatho—physiologicalprocessinChinesechildrenwithasthma.[KeywordslAsthma;Children;Interleukin;Evidence-basedmedicine;Meta—analysisI.,/angsuMedJ,October2005,31(10):741.742.f近年来儿童哮喘患病率有上升趋势
3、medicineofresearchontheseruminterleukinsinchildrenwithasthmaXUMeiyu,JIJianling.DepartmentofPediatrics,AffiliatedHospital,NantongUniversity,Nantong226001,CHlNA[AbstractlObjectiveToevaluatethesignificanceofinterleukin(IL)一4,II一6andIL-8measure—mentsinchildrenwithasthm&MethodTheanalysisofallrelatedlite
4、raturesinCBMdiscandChinesefulltextdatabasehasbeenmade.SelectioncriteriaweretheexaminationsofserumIL,4。IL一6andIL-8inChinesechildrenwithasthmaandcontro1groups.Aquantitativemeta—analysiswascarriedOUtbytworeviewsusingupdateinformationbasedoninclusionandexclusioncriteriafromthepapersavaila~ble.ResultsTh
5、econcentrationsofIL-4duringattackphaseandcatabaticphaseinthepatientsweresignificantlyhigherthanthoseinthehealthysubjects,whichwereincreasdby89.99ng/I(95CI47.13~132.84)and25.82ng/I(95CI15.78~35.86)(P6、1)and183.15ng/1(95C1104.58~261.72),whichwerehigherthanthoseinthehealthysubjects(P7、andIL-8playaroleinthepatho—physiologicalprocessinChinesechildrenwithasthma.[KeywordslAsthma;Children;Interleukin;Evidence-basedmedicine;Meta—analysisI.,/angsuMedJ,October2005,31(10):741.742.f近年来儿童哮喘患病率有上升趋势
6、1)and183.15ng/1(95C1104.58~261.72),whichwerehigherthanthoseinthehealthysubjects(P7、andIL-8playaroleinthepatho—physiologicalprocessinChinesechildrenwithasthma.[KeywordslAsthma;Children;Interleukin;Evidence-basedmedicine;Meta—analysisI.,/angsuMedJ,October2005,31(10):741.742.f近年来儿童哮喘患病率有上升趋势
7、andIL-8playaroleinthepatho—physiologicalprocessinChinesechildrenwithasthma.[KeywordslAsthma;Children;Interleukin;Evidence-basedmedicine;Meta—analysisI.,/angsuMedJ,October2005,31(10):741.742.f近年来儿童哮喘患病率有上升趋势
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