冠心病伴高尿酸血症临床的分析

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1、浙江大学硕日奸究生学位论文析，影响因素的重要性依次为性别，UA，LDL一。，TG，HDL，FBG，BMI，MS，在冠心病患者中，伴有高尿酸血症者冠状动脉的病变更严重且代谢综合征发生率更高，尿酸是冠心病发生、发展的重要因素，控制血尿酸水平具有临床意义。关键词:冠心病高尿酸血症冠状动脉造影Clinicalanalysisofcoronaryheartdisease(CHD)comPlicatedwithhyPeruricemia[Abstraet10bjective:肠analyseuricacideonCentrationandclini。alfeatureofcoronaryhear

2、tdiseasePatientsWhichwerediagnoseddefinitely.TostudythePrevaleneeofhyPerurieemiaofCHDPatients，andexPloretherelationshiPbetweenhyPerurieemiaandgender，age，CHD，diabetes，dysliPidaemia，CR，toguidePreventandtreatPatientsofCHDwithhyPeruricemia.Methods:Atotalof132Patientswhowereadmissioninzhejianguniver

3、sityMedica一eollageaffiliatedZndhospita一fromJan.ZoostoOct.ZOO7，aeeordingtourieaeideoneentration，normaluricacidgrouPandhyPerurieemiagrouP15determined，measureandregisterage，symPtom，、ignete，urieaeidconeentration，FB瓜ch()lesterol，andtheresultofeehoeardiograPhy，eoronaryangiograPhy认。rereeorded.All浙江人学硕

4、卜研究生学位论文statisticalanalyseswereusingSPSS15.0forWindows.QuantitativedatawereexPressedasmean士SD，iftheywerenormallydistributed.CorrelationswereassessedusinglogistieregressionmethodorPartialeorrelationwheneveraPProPriate.DatabetweengrouPswereassessedusingindependent一samplesTtestandx2test.Pva一ueswer

5、etwo一sidedandthatlessthan0.05waseonsideredsignificant.Results:Therewasnosignifieantlydifferencebetweenage，comParedtonormalurieacidgrouP，hyPerurieemiagrouPhashigherBMI，FBqTqLDL一c，malePatientshavehigheruricaeideoneentration，coronaryangiograPhyshowsthattherewasmuchmorediffuseandmulti一vessellesions

6、inhyPerurieemia.LogisticregressionanalysisshowedthatUAwasariskfaetorofCHD，obesity，FBqBMI，TqLDL一earealsoimPortantriskfaetor.Conclusions:InCHDPatients，there15moreseverelesionswithhyPerurieemia，andmoreMS，UA15animPortantfaetortooccurreneeanddeveloPmentofCHDand15ofeliniealsignifieancetoeontrolUA.Key

7、words:eoronaryheartdisease，hyPeruricemia，eoronaryangiograPhy浙江人学硕l:l口}究生学位论文月吐青随着我国经济的发展和人民生活水平的提高，慢性病业己成为主要死因，而其中又以心血管疾病最为突出[l。围绕心血管疾病的研究已经全方位的展开，目前认为高尿酸血症与糖尿病、高血压、高血脂、肥胖、吸烟一样是心血管疾病发生的独立危险因素【2-4]，近些年来对高尿酸血症的研究也开展较多，最早1951年首次提出尿酸可