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1、急诊联合检测CK-MB>cTnLMyo及NT-proBNP在急性冠脉综合症中应用价值罗海1.2张梅1.2(通讯作者)(1天津医科大学300070；2天津武警后勤学院附属医院300162)【摘要】FI的探讨血清CK・MB、cTnKMyo及NT-proBNP联合检测在急性冠脉综合症中临床应用价值。方法测定不稳定型心绞痛(UAP组)86例、非ST型抬高型心肌梗死(NSTEMI组)40例、ST抬高型心肌梗死(STEMI组)75例与同期健康体检人员40例作为对照组。所有入选对彖均检测血清CK・MB、cTnl、Myo及NT-proBNP并进行分析。结果血清CK・
2、MB、cTnl、Myo及NT-proBNP的水平随冠状动脉疾病病情的逐渐加重而递增，血清CK・MB、MYO及NT-proBNP水平与cTnl水平呈正相关，STEMI组血清标志物水平明显高于其他三组，具有显著性相关(P<0.01),NSTEACS者与对照组亦具有显著差异性(P<0.01)o结论血清CK・MB、cTnl、Myo及NT-proBNP联合检测在急性冠脉综合症的诊断,病情严重程度再梗死、预后判断及随诊等方面具有重要的临床意义。【关键词】冠心病急性冠脉综合征血清CK-MBcTnlMyoNT-proBNP【屮图分类号】R446【文献标识
3、码】A【文章编号】2095-1752(2013)33-0022-02TheapplicationvalueinemergencyofcombineddetectionofCK-MB,cTnl,MyoandNT-proBNPinacutecoronarysyndromeluoHai1,2zhangMei1,2(Authorforcorrespondence)(l.TianjinMedicalUniversity300070,China；2.DepartmentofEmergency,AffiliatedHospitalofLogisticUnivers
4、ityChinesePeople’sArmedPoliceForces,Tianjin300162,China)[Abstract]ObjectiveDiscussionoftheclinicalapplicationvalueinemergencyofcombineddetectionofCK-MB’cTnl’MyoandNT-proBNPinacutecoronarysyndrome.MethodsDeterminationof75patientswithSTelevationmyocardialinfarction(STEMIgro
5、up),40patientswithnonSTelevationmyocardialinfarction(NSTEMIgroup),86patientswithunstableanginapectoris(UAPgroup)andthecontrolgroupwith40casesisthesametimeofhealthphysicalexaminationpersonnel.AlloftheparticipantshavetodetectserumCK-MB,cTnl,MyoandNT-proBN^andyoumustanalyzetheresu
6、lts.ResultsTheresultsshowedthattheCK-MB,cTnl,MyoandNT-proBNPlevelsincreasedinpatientswithcoronaryarterydiseasegraduallyaggravated.SerumCK-MB,MYOandNT-proBNPlevelarepositivelycorrelatedwithcTnllevel.TheserummarkerlevelsingroupofSTEMIaresignificantlyhigherthantheotherthreegroups,
7、andthediffereneeissignificant(P<0.01),thedifferencesinNSTEACS,thecontrolgrouparealsosignificant(P<0.01).ConclusionsSerumCK-MB,cTnl,MyoandNT-proBNPcombineddetectionhaveimportantclinicalsignificanceinthediagnosisofACS,theseverityofthediseaseandprognosis.[Keywords]Acutecoron
8、arysyndromeCK-MBCTnlMyoNT-proBNP急性冠脉综合症的诊断主要依靠对临床症状的分析
