丹参对肝癌致鼠梗阻性黄疸时vegf表达的影响论文

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1、丹参对肝癌致鼠梗阻性黄疸时VEGF表达的影响论文【关键词】肝肿瘤EffectofDansheninjectiononVEGFexpressioninSDratsalignantobstructivejaundicecausedbyhepatocellularcarcinoma【Abstract】AIM:ToestablishmalignantbiliaryobstructionmodelofSDratsandtostudytheeffectsofDansheninjectiononthetumorsi

2、ze,inhibitionratesandmetastasisratesofhepatocellularcarcinomaandtheexpressionofvascularendotheliacellgroaandpericarcinomatissues,adjacentlobe(leftinternallobe)asodelsofSDratsadebyvaccinationoftransplantedtumorinliverneartheportahepatisacellline,etastasi

3、zedtoproximalmonbileductandcauseditsnarroeteroftransplantedtumor,inhibitionratesandmetastasisratesofhepatocellularcarcinomaandtheexpressionofVEGFincarcinomaandpericarcinomatissues,adjacentlobe(leftinternallobe)asade.RESULTS:Thediameterofthetumoretastasi

4、sratesofhepatocellularcarcinomaentofDansheninjectionparedeteroftumorentofDansheninjectionparedetastasisrate(59.7%and81.1%)ofhepatocellularcarcinomainratstreatedbyDansheninjectionilaraandpericarcinomatissuesentofDansheninjectionparedainSDratmodelsofmalig

5、nantbiliaryobstructionthroughreducingtheproliferationofhepatocarcinomacells,increasingthereversionofhepatocarcinomacellsanddoaandpericarcinomatissues.【Keyodels,animal;liverneoplasms;edUniv,2001;22（5）：350-351.［2］李晓明，汤钊猷，周洛，等.血管内皮细胞生长因子的表达与肝癌细胞浸润和转移的关系［J］

6、.中华肿瘤杂志，1998;20：12-14.LiXM,TangZY,ZhouL,etal.Expressionofvascularendothelialgroetastasisofhepatocellularcarcinoma［J］.ChinJOncolJanuary,1998;20:12-14.［3］梁勇,羊裔明,袁淑兰.丹参酮药理作用及临床研究进展［J］.中草药，2000;31（4）：304-306.LiangY,YangYM,YuanSL.Danshentongpharmacologicalef

7、fectsanddevelopmentofclinicresearch［J］.ChinTradHerbDrug,2000;31（4）：304-306.［4］夏荣龙，刘青光，潘承恩，等.丹参对肝癌致梗阻性黄疸时增殖细胞核抗原表达的作用［J］.西安交通大学学报(医学版)，2004；25（3）：247-249.