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1、普拉克索治疗早期帕金森病的效果论文许翔谢安木于永鹏李德全李冉【摘要】目的观察多巴胺受体激动剂普拉克索对早期帕金森(PD)病人的治疗效果。方法选择早期PD病人60例,随机分成美多芭组和普拉克索组,两组病人从小剂量开始渐增加剂量至症状稳定后维持治疗,采用改良ethodsSixtypatientsipexolegroupinrandom.Thedrugsloptomsaintenancetherapyonths.adopartherapy,thepatients’conditionuchimprovedthanpretherapy(F=76.619;q=11.85,17.31;P0.01)
2、;UPDRSscoreshoilarresult(F=39.032;q=9.34,11.85;P0.01).Asforadopargroupipexole(t=3.767,3.347;P0.01,0.05).ConclusionPramipexoleiseffectiveforimprovingthesymptomsofpatientsipexoleisnotasgoodasMadopar.KEYS1.53统计软件进行统计分析。2结果2.1两组治疗前后改良.北京:人民卫生出版社,2005:7.2SCHAPIRAAH.NeuroprotectionanddopamineagonistsJ
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5、n,anhedoniaandmotorfunctioninginParkinson’sdiseaseJ.JNeurolSci,2006,248(12):266270.10温洪波,张振馨,罗毅,等.普拉克索治疗帕金森病的多中心、随机、双盲、嗅隐亭对照临床疗效和安全性研究J.中华神经科杂志,2006,39(9):604608.11HOLLOA,2000,284(15):19311938.