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1、EpidemiologyofCardiovascularDiseaseMajorTypesofCardiovascularDisease(CVD)AdaptedfromMackayJ,MensahG,eds.TheAtlasofHeartDiseaseandStroke.TheWHOandtheUSCDC,2004.Coronaryheartdisease(CHD)RheumaticheartdiseaseCongenitalheartdiseaseStrokeAorticaneurysmanddi
2、ssectionDeepvenousthrombosisandpulmonaryembolismPeripheralarterydiseaseDeathsDuetoCHDandStrokeinEuropeAdaptedfromAllenderS,etal.EuropeanCardiovascularStatistics,2008.http://www.ehnheart.org/files/statistics%202008%20web-161229A.pdf.Accessed9November2008
3、.960,632494,188963,404744,5500200,000400,000600,000800,0001,000,0001,200,000CHDStrokeTotalNumberofDeathsinLatestAvailableYearMenWomenDeathsDuetoCVDvsOtherDiseasesinEuropeMenAdaptedfromAllenderS,etal.EuropeanCardiovascularStatistics,2008.http://www.ehnhe
4、art.org/files/statistics%202008%20web-161229A.pdf.Accessed9November2008.InjuriesandpoisoningAllothercausesStrokeCHDRespiratorydiseaseStomachcancerColorectalcancerOthercancerOtherCVDLungcancer17%12%7%11%6%2%2%11%11%21%InjuriesandpoisoningAllother
5、causesStrokeCHDRespiratorydiseaseStomachcancerColorectalcancerOthercancerOtherCVDLungcancer18%5%6%9%2%2%1%15%17%22%Breastcancer3%WomenCardiovascularMortalityIncreasesSharplyWithSerumCholesterolConcentrationinPatientsWithDiabetesAdaptedfromStamler
6、J,etal.DiabetesCare.1993;16:434–444.Deathsper10,000Person-Years100500CholesterolLevel150<180mg/dL200–219mg/dL240–259mg/dL280mg/dL(n=62,448)(n=1105)(n=75,122)(n=1038)(n=40,090)(n=529)(n=17,604)(n=353)NodiabetesDiabetesTheGapBetweenCHDPreventionGuidelines
7、andPracticeStatintherapyeffectivelyreducestheriskofmortalityandmajorcoronaryeventsinindividualswithhypercholesterolemiaorhyperlipidemicpatientswithorwithoutCHD.Nevertheless,thereisawidegapbetweentargetLDL-Clevelsestablishedbytreatmentguidelinesandthose
8、achievedinclinicalpractice.AdaptedfromWatersDD.AmJManagCare.2001;7:S138–S143;GrahamI,etal.EurJCardiovascPrevRehabil.2007;14(suppl2):E1–E40;NationalCholesterolEducationProgramExpertPanelonDetection,Evaluation,andTreatmentof