5、ectlyshowactivitychangeofCOX. Results WithLPSstimulation,theexpressionofPIMs,COX-2mRNA,enzymeproteinandthelevelsofPGE2wereincreasedmorerapidlythanthoseinthecontrolgroup(P<0.01).PositivecorrelationwasfoundbetweentheexpressionofCOX-2enzymeproteinandthecontentofPGE2(r=0.94,P<0.01). Conclusions Af