欢迎来到天天文库
浏览记录
ID:15214918
大小:33.50 KB
页数:7页
时间:2018-08-02
《布托啡诺超前镇痛对肋间神经阻滞效果的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、布托啡诺超前镇痛对肋间神经阻滞效果的影响【摘要】目的评价布托啡诺超前镇痛对罗哌卡因肋间神经阻滞效果的影响。方法选择40例拟在肋间神经阻滞下行乳房病损切除术的女性患者,采用双盲法随机分成试验组(A组)和对照组(B组),每组各20例:A组患者于肋间神经阻滞前5min静脉推注布托啡诺20μg/kg,B组于肋间神经阻滞前5min静脉推注安慰剂(生理盐水)。两组均施行罗哌卡因肋间神经阻滞。对术中麻醉满意程度进行评价,记录麻醉起效时间、麻醉维持时间及恶心呕吐等不良反应发生率,分别于术后1、4、12、24h采用“视觉模拟评分法(VAS)”进行疼痛评分。结果术中麻醉满意程
2、度A组优于B组,术后4、12h时疼痛评分A组显著低于B组(P<0.05),麻醉维持时间A组明显长于B组,两组比较差异有统计学意义(P<0.01)。结论术前静脉推注布托啡诺具有一定的超前镇痛效果,能够增强罗哌卡因肋间神经阻滞效果,延长术后镇痛时间,不良反应少,值得临床采用。 【关键词】布托啡诺;超前镇痛;肋间神经阻滞;罗哌卡因 【Abstract】ObjectiveToevaluatetheclinicalefectsofButorphanolpreempitiveanalgesiaonintercostalnerveblockwit
3、hropivacaine.MethodsApplingdoubleblindmethod,40adultmalepatientsundergoingbreastlesionresectionoperationonintercostalnerveblockweredividedrandomlyinto7testgroup(groupA)andcontrolgroup(groupB)with20caseseach.Everygroupreceivedintercostalnerveblockwithropivacaine.GroupA(testgroup)in
4、travenouslyinjectedthepatientwithbutorphanol20μg/kgat5minutesbeforeintercostalnerveblock.GroupB(controlgroup)intravenousinjectedthepatientwithplacebo(physiologicalsaline)at5minbeforeintercostalnerveblock.Thedegreeofintraoperativeanesthesiasatisfactionwasevaluated.Theonsettimeofane
5、sthesia,thedurationtimeofnerveblockade,theadversereaction(egnauseaandvomiting)andVAS(thevisualanaloguescale)scoresat1,4,12,24hoursafteroperativewererecorded.ResultsThedegreeofintraoperativeanesthesiasatisfactioningroupAwasbetterthanthatingroupB(P<0.05),Thedurationofnerveblockad
6、eingroupAwasobviouslylongerthanthatingroupB(P<0.01).ThescoresofVASat4、12hpostoperativeingroupBwashigherthanthatingroupA(P<0.05).ConclusionIntravenouslyinjectingbutorphanolbeforeoperativehavetheefectofpreempitiveanalgesia.Itcanpotentiatetheefectsofintercostalnerveblockwithrop
7、ivacaineandprolongthetimeofpostoperativeanalgesiaandlittleadversereaction,deservetheclinicadoption.7 【Keywords】Butorphanol;Preempitiveanalgesia;Intercostalnerveblock;Ropivacaine 超前镇痛是伤害性刺激作用于机体之前采取一定的措施,防止神经中枢敏感化,减少和消除伤害引起的疼痛[1]。布托啡诺是混合型阿片受体激动-拮抗剂,其镇痛效应强,镇痛时间久,呼吸抑制和成瘾性发生率较低。本
8、研究旨在观察布托啡诺超前镇痛对肋间神经阻滞效果、麻醉维持时间、术后
此文档下载收益归作者所有