对比分析头颈部鳞状细胞癌petct与petmr特征

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1、对比分析头颈部鳞状细胞癌PET/CT与PET/MR特征白乐程勇唐勇进凌雪英暨南大学附属第一医院医学影像中心目的探讨头颈部鱗状细胞癌（ILNSCC）的PET/CT及PET/MR特征。方法纳入未经抗肿瘤治疗的头颈部鳞状细胞癌患者40例，所有患者均接受PET/CT及头颈部MR检查。由2名观察者独立观察PET阳性病灶，包括阳性原发灶及阳性淋巴结；并对PET/CT、PET/MRT1WI及PET/MRT2WI的图像质量、融合准确度、病灶清晰度、病灶特征等进行评分。分析2名观察者间的一致性。结果40例患者共90个PET阳性病灶，包括阳性原发

2、灶40个、阳性淋巴结50个。PET/CT、PET/MRT1WI及PET/MRT2WI在图像质量及融合准确度方而差异均无统计学意义（P均＞0.05）;在显示阳性原发灶及阳性淋巴结的清晰度方面，PET/MRT1W1及PET/MRT2W1均优于PET/CT（P均〈0.05）。40个阳性原发灶中,PET/MRT2WI对29个原发灶的特征显示多于PET/CT，4个原发灶与PEVCT相仿，7个原发灶较PET/CT少。结论PET/MR在11NSCC诊断屮的应用是可行的，在显示头颈部局部病灶时较PET/CT更具优势。关键词：正电了发射型体层摄

3、影术;磁共振成像;癌，鱗状细胞;头颈部肿瘤;研究方向：医学影像诊断。ComparativeanalysisofPET/CTandPET/MRimagecharacteristicsofheadandnecksquamouscellcarcinomaBAILeCHENGYongTANGYongjinLINGXueyingMedicalImagingCenter，theFirstAffiliatedHospitalofJinanUniversity;Abstract：ObjectiveToinvestigatePET/CTandP

4、ET/MRcharacteristicsofheadandnecksquamouscellcarcinoma(HNSCC).MethodsTotally40patientswithHNSCCunderwentwholebody18F-FDGPET/CTandMRscansofheadandneckbeforeanti-tumortreatment.PETpositivelesionsofHNSCC,includingprimarylesionsandlymphnodeswereevaluatedby2radiologistsi

5、ndependently.Thentheimagingquality,fusionquality,lesionconspicuityandlesioncharacteristicswereassessedbasedonPET/CT,PET/MRT1WIandPET/MRT2WI.ResultsNinetyPETpositivelesionsinall40patientswereevaluated,including40primarylesionsand50lymphnodes.Similarimagingqualityandf

6、usionqualityofPET/CT,PET/MRT1WIandPET/MRT2WIwereobtainedwithoutstatisticaldifference(bothP〉0.05).Forthelesionconspicuity,PET/MRT1WTandPET/MRT2WTdemonstratedsignificantlybetterthanPET/CTinpositiveprimarylesionsandlymphnodes(allP<0.05).Forthecharacteristicsofpositivep

7、rimarylesions,PET/MRT2WIprovidedmoreinformationthanPET/CTin29lesions,equaltoPET/CTin4lesions,andlessthanPET/CTin7lesions.ConclusionTheapplicationofPET/MRinHNSCCisfeasible,beingsuperiortoPET/CTinindicationoflesionsinheadandneckarea.Keyword：Positronemissiontomography;

8、Magneticresonanceimaging;Carcinoma;squamouscell;Headandneckne-oplasms;头颈部恶性肿瘤的发病率居全身恶性肿瘤的前10位U1,其屮多数为起源于黏膜上皮的鱗状细胞癌m。由于尖颈部解剖结构复杂，因此早期诊断尖颈部肿