磺达肝葵钠解读电子教案.ppt

《磺达肝葵钠解读电子教案.ppt》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、磺达肝葵钠解读Fondaparinuxisgivenatafixeddoseof2.5mgdailyforthromboprophylaxisandforthetreatmentofACSFortreatmentofDVTorpulmonaryembolism5mg:weight<50kg7.5mg:weight50to100kg10mg:weighing>100kg.routinecoagulationmonitoringisnotrecommendedpatientswithmoderaterenalinsufficiency(ie,CrCl30-50

2、mL/min),thedoseoffondaparinuxshouldbereducedby50%contraindicatedinpatientswithrenalinsufficiency(CrCl<30mL/min)2.1.8—2.1.11房颤患者抗凝的选择AspirinClopidogrelOralanticoagulationremarksDabigatranVKAlowrisk（0）IntermediateRisk(1)UnableforOAhighrisk(≥2)UnableforOAAFandmitralstenosisUnableforO

3、ADabigatran150mgbid推荐应用：更好的选择：PerioperativeManagementserialimagingofth（2C）epatientstemporaryinterruptionofaVKAbeforesurgerystoppingVKAsapproximately5daysbeforesurgery（1C）BridgingAnticoagulation1.mechanicalheartvalve2.Atrialfibrillation3.HighriskofthromboembolismBridgingAnticoagula

4、tionBridginganticoagulationastheadministrationofashort-actinganticoagulantSubcutaneous(SC)LMWHorIVUFH10-to12-dayduringinterruptionofVKAtherapyPreventionofVTEinHospitalizedAcutelyIllMedicalPatientsserialimagingoftheacutelyillhospitalizedmedicalpatientsinitialtreatmentwithparenteral

5、anticoagulation（1B）LMWH（1B）fondaparinux(1B)LDUH（1B）PreventionofVTEinNonorthopedicSurgicalPatientsserialimagingofthegeneralandabdominal-pelvicsurgerymoderateriskforVTE+notathighriskformajorbleedinglow-doseaspirinFondaparinux(2C)LMWH(2B)LDUH(2B)IPC（2C)2.1PreventionofVTEinOrthopedicS

6、urgeryPatientsInacutePEpatients,whenuseathrombolyticagentInacutePEpatients,whenuseathrombolyticagentTotalHipArthroplasty(THA)orTotalKneeArthroplasty(TKA)minimum10to14daysLMWHispreferable(2B)LMWHfondaparinuxapixaban、dabigatran、rivaroxabanlow-doseUH、VKA、aspirin(1B）2.1PreventionofVTE

7、inOrthopedicSurgeryPatientsInacutePEpatients,whenuseathrombolyticagentInacutePEpatients,whenuseathrombolyticagentHipfracturesurgery(HFS)minimum10to14daysLMWHispreferable(2B)LMWHFondaparinuxLDUHVKAAspirin(1B）2.1急性下肢DVT的抗凝方案的选择serialimagingofthepatientswithacuteDVTofthelegtreatedwit

8、hVKAtherapyinitialtreatmentwithpa