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时间:2020-05-24
《阿魏酸钠对大鼠肝纤维化的作用.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
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2、I’华^;l化杂盎'@世界华人消化杂志2014年4月28日;22(12):1676—1681wcjd@wjgnet.tomISSN1009—3079(print)ISSN2219—2859(online)歼究快报lID。a亿le.ION阿魏酸钠对大鼠肝纤维化的作用杨娟,徐胜南,王敏,彭丽萍,周琦一背景资料杨娟.成都市第一人民医院消化内科四川省成都市610041ligation,respectively.Biochemicalparameters肝硬化是一种弥徐胜南,彭萍,:华宁科技大学同济医学院附属同济wereme
3、asured.Bodyweight,liverweightand百引錾托一乐引严呈王譬敏.华中臻科技大学同济医学院300附30属同济医院急诊科湖北1i一v一eri“ndexwereco—mpar—edbetweengroups.’主鼻雍.‘痞,肝省武汉市430030Pathologicalcharacteristicsoflivertissueswere磐发展杨婕,师,,毒萼事化菩系品统疾病的研究翌·徐-睢南、osb⋯servlecdtrboyn~ompitcircoaslcompiycroscopyandtransm
4、is一,andtheintegrated‘王敏及彭丽萍完成:数据分析及写作由杨娟完成:周琦审校sorbanceofhepatica-smoothmuscleactinwas通讯作者:周琦,副整授,430030,湖解放大道1095determinedbyimmunohistochemistry.zhouqi@tjh.mu.educaRESULTS:Biochemicalparametersdidnot电话:027—83663334收稿日期:2014-01—26修回日期:2014-03—01differbetweenthe
5、modelgroupandtreat-接受日期:2014—03—18在线出版日期:2014-04—28mentgroup.Liverindexinthemodelgroupincreasedcomparedwithcontrolratsf7.83%±0.57%vs4.05%±0.17%,P<0.011;aftertreat—Effectsofsodiumferulateonment,theindexdecreasedsignificantly(7.08%士liverfibrosisinexperimental0.68%
6、vs7.83%±0.57%,P<0.05).Pathologicalcirrhoticratsobservationrevealedthatthedegreeoffibrosisandseverityofhepatocytedamageinthetreat—3uanYang,Sheng—NanXu,MinWang,U—PingPeng,mentgroupwerelowerthanthoseinthemodelQiZhougroup.Hepatic仪一SMAcontentinthemodelgroupwassignifi
7、cantlyhigherthanthatinthe3uanYang,DepartmentofGastroenterologtheFirstcontrolgroupr113224.74土45518.79vs4197.80士People’sHospitalofChengdu.Chengdu6l0041.Sichuan1364.97,P<0.011.AftertreatmentwithsodiumProvince,Chinaferulate,hepatic0【一SMAcontentdecreasedinSheng-NanXu
8、,Li-PingPeng,QiZhou,DepartmentofGastroenterology,TongjiHospita1.Wuhan430030.HubeithetreatmentgroupcomparedwiththemodelProvince,Chinagroupr46451.65±15600.56口s113224.74±MinWang,DepartmentofEmergencyMedicine,Ton~jiHos—45518.79,P<0.05).pitalofTongjiMedicalCollege.Hu
9、azhongUniversityofSci。enceandTechnology,an430030.HubeiProvince.ChinaSupportedby:NationalNatura1ScienceFoundationofCONCLUSION:Sodiumferulatehasatherapeu—China.No.81070
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