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1、Friedel-CraftsAcrylationReactionFriedel-CraftsAlkylationReactionGabrielSynthesisGattermann-KochReactionHarriesOzonideReactionHeckReactionSuzukiReaction:SuzukiReaction’smechanism:StilleReaction:Stillereaction’smechanismSynthesisofArylandVinylStannanes:SynthesisofArylandVinylStannanes:
2、FukuyamacouplingThepalladium-catalyzedcouplingoforganozinccompoundswiththioesterstoformketones.Thisreactiontoleratesavarietyoffunctionalgroupsduetothelowreactivityoftheorganozincreagents.H.Tokuyama,S.Yokoshima,T.Yamashita,S.-C.Lin,L.Li,T.Fukuyama,J.Braz.Chem.Soc.,1998,9,381-387.Fukuy
3、amacoupling’sMechanismOxidativeadditionofthethioesterisfollowedbytransmetalationfromthezinccompound.Reductiveeliminationleadstothecoupledproduct.TheNegishicoupling,publishedin1977,wasthefirstreactionthatallowedthepreparationofunsymmetricalbiarylsingoodyields.Theversatilenickel-orpall
4、adium-catalyzedcouplingoforganozinccompoundswithvarioushalides(aryl,vinyl,benzyl,orallyl)hasbroadscope,andisnotrestrictedtotheformationofbiaryls.NegishiCouplingNegishiCoupling’sMechanismN.Hadei,E.A.B.Kantchev,C.J.O'Brien,M.G.Organ,Org.Lett.,2005,7,3805-3807.S.Huo,Org.Lett.,2003,5,423
5、-425.A.Lützen,M.Hapke,Eur.J.Org.Chem.,2002,2292-2297KumadaCouplingTheKumadaCouplingwasthefirstPdorNi-catalyzedcrosscouplingreaction,developedin1972.KumadaCoupling’sMechanismL.-M.Yang,L.-F.Huang,T.-Y.Luh,Org.Lett.,2004,6,1461-1463.Hell-Volhard-ZelinskyReactionHenryReactionHofmannReact
6、ionHorner-Emmons-WadsworthReactionJacobsenEpoxidationJonesOxidationKnoevenagelCondensationKolbe-SchmittReactionKucherovReaction
