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1、IntracranialCysts-Radiologic-PathologicCorrelationandImagingApproachRadiology:Volume239:Number3-June2006AnneG.Osborn,MDMichaelPreece,MDClassificationOriginandpathogenesiscystsNormaland/orvariantCongenitalTraumaticand/orvascularinfectiousTumor–associatednonneoplasticChoroidplexus(xanthogra
2、nuloma),enlargedperivascularspaces(PVSs),ependymal,neuroglial,pinealArachnoid,colloid,epidermoid,dermoid,neurenteric,RathkecleftPorencephalic,neurocysticerosis,hydatid,otherparasiticsystsMeningioma(withtrappedcerebrospinalfluid),schwannoma(witharachnoidcyst),pituitaryadenoma(withenlargedP
3、VSs),craniopharyngioma(withenlargedPVSs)Thisstablenotincludecysticandnecroticneoplasms,aswellasbrainabscessesChoroidPlexusCysts(CPCs)PathologicFindingsNonneoplasticepithelial-linedcystsofthechoroidplexusMostcommonofallintracranialneuroepithelialcysts,occurringinupto50%ofautopsycasesMostar
4、ebilateralandlocatedinthelateralventricularatriaMostCPCsareasymptomatic,typicallyinneonatesandolderadultsSymptomaticlesionsareraresincetheatriatypicallyenlargetoaccommodatethecystTransversegraphicrepresentationshowsmultiplecysticmassesinthechoroidplexusglomi(arrows).MostCPCsareactuallydeg
5、enerativexanthogranulomasPathologicFindingsOccurwhenlipidaccumulatesinthechoroidplexusfromdegeneratingand/ordesquamatingchoroidepitheliumCanbealmostentirelycystic,nodular,orpartiallycystic.Appearasnodular,yellowishgraymasseswithintheglomusofthechoroidplexus.Mostaresmall,measuring2–8mmindi
6、ameter.Cystsgreaterthan2cmarerare.ChoroidPlexusCysts(CPCs)ChoroidPlexusCysts(CPCs)MicroscopicMicrocystscontainingnestsoffoamylipid-ladenhistiocytesChronicinflammatorylymphocyticandplasmacellinfiltrates,cholesterolclefts,hemosiderin,andperipheralpsammomatouscalciumChoroidPlexusCysts(CPCs)C
7、TIso-toslightlyhyperattenuatedonnonenhancedCTscanscomparedwithCSFPeripheralcalcificationiscommonEnhancementvariesfromnonetostrikingChoroidPlexusCysts(CPCs)MRIIso-orhyperintenseonprecontrastT1-weightedMRimagescomparedwithCSFandshowrimornodularcontrastenhancementUsual