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时间:2020-06-21
《游泳运动对慢性支气管炎大鼠肺组织MDA和SOD的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、临历云研究Linchuangyanjiu《中国医学创新》第11卷第25期(总第307期)2014年9月游泳运动对慢性支气管炎大鼠肺组织MDA和SOD的影响况晓【摘要】目的:探讨有氧运动对慢性支气管炎大鼠肺组织MDA含量和SOD活性的影响。方法:将sD大鼠30只按照随机数字表法分为正常组、模型组和运动模型组,每组10只。采用改良烟熏法建立慢性支气管炎大鼠模型,并对慢性支气管炎模型大鼠进行8周游泳运动干预,检测运动干预后各组大鼠肺组织MDA和SOD含量变化。结果:与正常组相比,慢性支气管炎模型组大鼠体重显著降低(P<0.05),运动模型组体重降低不明显。慢性支气管炎模型组大鼠肺组织和支
2、气管肺泡灌洗液(BALF)中MDA含量明显高于正常对照组和运动模型组(P3、ofChina。2014.11(25):048—051【Abstract】Objective:ToinvestigatetheeffectsofswimmirIgonMDAandSODoflungtissueinchronicbronchitisrats.Method:ThirtySDratswererandomlydividedintothreegroups:thenormalgroup,themodelgroupandtheexercise-modelgroup,10ratsineachgroup.Modifiedsmokedmethodwasusedtoestablishth4、eratchronicbronchitismode1.Theratsofchronicbronchitisweretrainedfor8weeksinswimmingpools.ChangesofMDAandSODlevelinlungtissueofratsineachgroupweredetectedafterexerciseintervention.Result:Comparedwiththenormalcontrolgroup,bodyweightofratsinchronicbronchitisgroupdecreasedsignificantly(P<0.05),but5、theweightlosswasnotobviousinexercisegroup.TheMDAoflungtissueandbronchialalveolarlavagefluid(BALF)inchronicbronchitisratsweresignificantlyhigherthanthatofnormalcontrolgroupandexercisegroup(P<0.05).Atthesametime,theSODoflungtissueandBALFinchronicbronchitisgroupwassignificantlylowerthanthatinthen6、ormalcontrolgroupandexercisegroup(P<0.05).Conclusion:8-weekswimmingexercisecanincreasetheSODactivityandreducetheMDAinlungtissueofchronicbronchitisrats,whichincreasetheabilityofantioxidantinjury,relievetheinflammation,improvelungfunction.【Keywords】Chronicbronchitis;Lungtissue;SwimmingFirst-auth7、or’Saddress:TianmenHospitalofTraditionalChineseMedicine,Tianmen431700,Chinadoi:10.3969/j.issn.1674—4985.2014.25.017慢性支气管炎是常见的呼吸系统疾病,在中老年但目前研究中对慢性支气管炎的治疗主要是进行抗炎、人中发病率较高,且病程长、反复发作,不仅严重危镇咳、平喘作用的药物治疗,也有少量的其他方式的害患者个人身体健康,同时还对患者生活造成一定的治疗,如针灸、
3、ofChina。2014.11(25):048—051【Abstract】Objective:ToinvestigatetheeffectsofswimmirIgonMDAandSODoflungtissueinchronicbronchitisrats.Method:ThirtySDratswererandomlydividedintothreegroups:thenormalgroup,themodelgroupandtheexercise-modelgroup,10ratsineachgroup.Modifiedsmokedmethodwasusedtoestablishth
4、eratchronicbronchitismode1.Theratsofchronicbronchitisweretrainedfor8weeksinswimmingpools.ChangesofMDAandSODlevelinlungtissueofratsineachgroupweredetectedafterexerciseintervention.Result:Comparedwiththenormalcontrolgroup,bodyweightofratsinchronicbronchitisgroupdecreasedsignificantly(P<0.05),but
5、theweightlosswasnotobviousinexercisegroup.TheMDAoflungtissueandbronchialalveolarlavagefluid(BALF)inchronicbronchitisratsweresignificantlyhigherthanthatofnormalcontrolgroupandexercisegroup(P<0.05).Atthesametime,theSODoflungtissueandBALFinchronicbronchitisgroupwassignificantlylowerthanthatinthen
6、ormalcontrolgroupandexercisegroup(P<0.05).Conclusion:8-weekswimmingexercisecanincreasetheSODactivityandreducetheMDAinlungtissueofchronicbronchitisrats,whichincreasetheabilityofantioxidantinjury,relievetheinflammation,improvelungfunction.【Keywords】Chronicbronchitis;Lungtissue;SwimmingFirst-auth
7、or’Saddress:TianmenHospitalofTraditionalChineseMedicine,Tianmen431700,Chinadoi:10.3969/j.issn.1674—4985.2014.25.017慢性支气管炎是常见的呼吸系统疾病,在中老年但目前研究中对慢性支气管炎的治疗主要是进行抗炎、人中发病率较高,且病程长、反复发作,不仅严重危镇咳、平喘作用的药物治疗,也有少量的其他方式的害患者个人身体健康,同时还对患者生活造成一定的治疗,如针灸、
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