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时间:2020-06-03
《昆明市青少年变应性鼻炎患者变应原谱分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、第19卷第5期中国耳鼻咽喉颅底外科杂志V0J.19N0.52013年1O月ChineseJournalofOtorhinolaryngology—SkIlIlBaseSurgery0ct.2013DOI:10.11798/j.issn.1007—1520.201305005·论著·昆明市青少年变应性鼻炎患者变应原谱分析高映勤,马静,陆涛,林垦(昆明市儿童医院耳鼻咽喉科,云南昆明650034)摘要:目的调查昆明地区变应性鼻炎(allergicrhimtis,AR)患者的变应原谱。方法将具有典型AR临床症状的567例患者按年龄分为9组,采用l3
2、种当地常见变应原对不同性别年龄组患者进行变应原分布情况分析。结果①女性患者粉尘螨、户尘螨、蒿属花粉和法国梧桐的过敏阳性率显著高于男性(t=2.701,P=0.012)。②不同年龄组中,过敏原分布比较差异无统计学意义(P>0.05)。③93.5%患者检测出过敏原,其中2.1%患者对一种过敏原过敏,91.4%患者为多重过敏。在粉尘螨与户尘螨两种过敏原中,5.46%仅对其中一种尘螨过敏,85.4%同时对两种尘螨过敏。④平均过敏原的个数随年龄增大而增多(F=8.738,P=0.012),而各年龄组男女性别间比较差异无统计学意义(F=1.873,P=
3、0.400)。结论尘螨、蒿属花粉和法国梧桐是昆明地区最常见的过敏原,随年龄增长,患者的人均变应原个数增多。关键词:变应性鼻炎;变应原,粉尘螨,户尘螨;皮肤点刺试验中图分类号:R765.21文献标识码:A文章编号:1007—1520(2013)05—0403—06SpectrumofsensitizedallergensinpediatricpatientswithallergicrhinitisinKunmingGAOYing—qin,MAJing,LUTao,etal(DepartmentofOtorhinolaryngology,Chi
4、ldren’sHospitalofKunmingCity,Kunming650034,China)Abstract:ObjectiveToinvestigatethemainallergensinchildrenwithallergicrhinitis(AR)inKunming.MethodsThi~eenkindsofcommonallergensinKunmingwereusedforperformingskinpricktest(SPT)in567childrensufferingfromsuspectedAR.AUthechildr
5、enweredividedinto9agegroupsand2gendergroups.Andthedistributionsofdifferentallergensinallthegroupswereanalyzed.Results①ThepositiveratesofSPTforDermatophagoidesfayinae(Derf),Dermatophagoidespteronyssinus(DerP),Mugwort,Platanusinfemalegroupweresignificantlyhigherthanthoseinma
6、legroup(t=2.701,P=0.012).②Thediferencesofallergensdistributionsamongdifferentagegroupswerestatisticallyinsignificant(P>0.05).③Thetotalpositiveratewas93.5%.including2.1%withsinglepositiveallergenand91.4%withmuhipleallergens.AsforDerfandDerP,therateswithsinglepositiveallerge
7、nanddualpositiveallergenswere5.46%and85.4%respectively.(Theaveragenumbersofpositiveallergenswereincreasingwithincreasingage(F=8.738,P=0.012),whilethediferencesbetweendifferentgenderswereinsignificantineachagegroup(F=1.873,P=0.400).ConclusionsDustmites,MugwortandPlatanusare
8、identifiedasthemostconunonallergensamongpediatricpatientswithARinKunming.Theaveragenumber
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