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时间:2020-06-05
《脑微出血磁敏感加权成像检出情况及其与认知功能的关系.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、(~ChineseGeneralPractice·2532·∞鞴礴gl峨罄ig孵鼹4童·全科医生技能发展·脑微出血磁敏感加权成像检出情况及其与认知功能的关系肖桂荣,孙新芳,王赵伟【摘要】目的探讨磁敏感加权成像(SWI)对脑微出血(CMBs)的检出情况及CMBs对认知功能的影响。方法选取2012年1月_20l3年8月在绍兴市人民医院神经内科住院及门诊行SWI检查确诊CMBs的患者50例为CMBs组,另选取同时期性别、年龄、文化水平相匹配的SWI未见微出血灶的体检者44例为对照组,使用蒙特利尔认知评定量表(MoCA)评价其认知功能,比较两组患者MoCA评分情况及不同级别
2、和部位的CMBs引起的认知功能障碍情况。结果CMBs在sWI上主要表现为脑实质内边界清晰的小圆形低信号影。CMBs组患者MoCA总分、视空间执行能力、命名、注意力、语言、抽象能力、记忆力、定向力均低于对照组(P<0.05)。与对照组比较,轻度CMBs组、中度CMBs组、重度cMBs组MoCA总分、视空间执行能力、抽象能力、记忆力评分降低,中度CMBs组、重度CMBs组命名、注意力、语言评分降低(P<0.05);与轻度cMBs组比较,中度cMB8组、重度cMBs组MoCA总分、注意力、抽象能力、记忆力评分降低,重度CMBs组视空间执行能力、语言评分降低(P<0.05)
3、;与中度CMBs组比较,重度cMBs组MoCA总分、视空间执行能力、注意力、语言、记忆力评分降低(P<0.05)。Spearman相关分析显示:CMBs数量与MoCA总分、视空间执行能力、注意力、语言、抽象能力、记忆力评分呈负相关(P<0.05);皮质一皮质下CMBs与MoCA总分、视视空间执行能力、注意力、语言、记忆力评分呈负相关(P<0.05);基底核和丘脑CMBs与MoCA总分、语言评分呈负相关(P<0.05);脑干和幕下CMBs与MoCA总分、视空间执行能力评分呈负相关(P4、和部位的CMBs引起的认知功能障碍不同。【关键词】脑出血;磁共振成像;认知;蒙特利尔认知评估量表【中图分类号】R743.34【文献标识码】Adoi:l0.3969/j.issn.1007—9572.2014.21.029肖桂荣,孙新芳,王赵伟.脑微出血磁敏感加权成像检出情况及其与认知功能的关系[J].中国全科医学,2014,17(21):2532—2535.[www.chinagp.net]TheDetectionofCerebralMicrobleedsbySusceptibilityWeightedImagingandtheRelationshipbetween5、CerebralMi·crobleedsandCognitiveFunctionXIAOGui—rong,SUNXin一ng,WANGZhao—wei.DepartmentofNeurology,Shaox—ingPeople5Hospital,Shaoxing312000,China【Abstract】ObjectiveToinvestigatethedetectionofcerebralmicrobleeds(CMBs)bysusceptibilityweightedima-ging(SWI),andinfluenceofCMBsoncognitivefunct6、ion.Methods50patientswhowereactuallydiagnosedwithCMBsbySWIininpatientandoutpatientdepartmentsofneurology,ShaoxingPeoplesHospitalfromJanuary2012toAugust2013,wereselectedasCMBsgroup,duringthesameperiod,while44sex一,age—andeducationlevel—matchedphysicalexaminationpeoplewhowerenotf0undtohav7、eCMBsbySWI,wereselectedascontrolgroup,theircognitivefunctionwasevaluatedbyMoCAratingscale,MoCAscorewerecomparedbetweenthetwogroupsandthecognitivedysfunctioncausedbyCMBsofdifferentregionsanddiferentdegrees.ResultsSWIimagingfeaturesofCMBsweresharplymarginatedsmallroundlowsignalimagesin
4、和部位的CMBs引起的认知功能障碍不同。【关键词】脑出血;磁共振成像;认知;蒙特利尔认知评估量表【中图分类号】R743.34【文献标识码】Adoi:l0.3969/j.issn.1007—9572.2014.21.029肖桂荣,孙新芳,王赵伟.脑微出血磁敏感加权成像检出情况及其与认知功能的关系[J].中国全科医学,2014,17(21):2532—2535.[www.chinagp.net]TheDetectionofCerebralMicrobleedsbySusceptibilityWeightedImagingandtheRelationshipbetween
5、CerebralMi·crobleedsandCognitiveFunctionXIAOGui—rong,SUNXin一ng,WANGZhao—wei.DepartmentofNeurology,Shaox—ingPeople5Hospital,Shaoxing312000,China【Abstract】ObjectiveToinvestigatethedetectionofcerebralmicrobleeds(CMBs)bysusceptibilityweightedima-ging(SWI),andinfluenceofCMBsoncognitivefunct
6、ion.Methods50patientswhowereactuallydiagnosedwithCMBsbySWIininpatientandoutpatientdepartmentsofneurology,ShaoxingPeoplesHospitalfromJanuary2012toAugust2013,wereselectedasCMBsgroup,duringthesameperiod,while44sex一,age—andeducationlevel—matchedphysicalexaminationpeoplewhowerenotf0undtohav
7、eCMBsbySWI,wereselectedascontrolgroup,theircognitivefunctionwasevaluatedbyMoCAratingscale,MoCAscorewerecomparedbetweenthetwogroupsandthecognitivedysfunctioncausedbyCMBsofdifferentregionsanddiferentdegrees.ResultsSWIimagingfeaturesofCMBsweresharplymarginatedsmallroundlowsignalimagesin
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