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时间:2020-05-24
《腹腔镜辅助特殊部位小肝癌的射频治疗.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、20肝胆外科杂志2014年2月第22卷第1期JournalofHepatobiliarySurgery,Vol,22,No.1,Feb.2014腹腔镜辅助特殊部位小肝癌的射频治疗刁广浩,张绍庚,王兆海,洪智贤,高远,罗开国,丁同领【摘要】目的探讨腹腔镜辅助射频消融术治疗特殊部位小肝癌的可行性、安全性及优势,并评估其疗效。方法为65例合并不同程度肝硬化肝癌患者、79个特殊部位肿瘤行腹腔镜辅助射频消融术(1aparoscopicradiofrequencyablation,LRFA),肿瘤位于肝脏表面、近膈顶、肝门部、邻近胆囊、胃肠等空腔脏器,平均直径为2.162±0.6417em。结
2、果65例均成功施行LRFA治疗,单个病灶平均布针为3次,平均LRFA时间为39.2±7.0min,所有病例均未出现大出血、胆漏、胃肠道烧灼、膈肌损伤、肝功能衰竭等严重并发症。术后住院4—11天,平均8.3d。术后一月复查,34例术前血清AFP阳性的患者均下降到正常范围、超声检查或螺旋cT增强扫描病灶完全坏死率达100%。随访1—24个月,3例发现肝内新病灶,复发时间为5~22个月,再次采用腹腔镜下射频消融治疗。结论LRFA为特殊部位小肝癌患者提供了安全、有效、经济、微创的治疗方法,具有良好的临床应用价值。【关键词l肝肿瘤;射频消融术;腹腔镜检查【中图分类号】R735.7【文献标识码
3、】A【文章编号】1006-4761(2014)0l-0020-05Laparoseopicradiofrequencyablationforthesmalllivercancerofspecialparts(DIAOGuang—hao,ZHANGShao—g彻,WANGZhao—hai,eta1.J.DepartmentofHepatobiliarySurgery,ClinicalMedicineSchool,FuzhouGeneralHospital,FujianMedicalUniversity,Fuzhou350025,China;2.DepartmentofHepatobi
4、liarySurgery,the302MilitaryHospitalofChina,Beng100039,China)【Abstract】ObjectiveToexplorethefeasibility,securityandadvantageoflaparoscopicradiofrequencyablation(LRFA)forthesmalllivercancerofspecialpartsandtoevaluatethecurativeefect.Methods65patientswhosuferedlivercancerwith79tumornodulesonspeci
5、alpartsweretreatedbyLRFA.Thehepaticlesionswithameandiameterof2.162±0.6417amwerelocatedinthesur-faceoftheliver,adjacenttOdiaphragmaticdome,fossaetisheransversalpatis,gallbladder,orgastrointestinaltract.ResultsLRFAtherapywassuccessfullyperformedinallpatients.ThemeanLRFAtimeperlesionwas39.2±7.0mi
6、nutes.themeanRFAtimesforasinglenoduleis3.Noseverecomplicationssuchasbleeding,bileleakage,gastrointestinaltractdamage,diaphragmaticinjuryandliv—erfunctionfailuredevelopedafteroperations.Patientshospitalized4-11days,withanaverageof8.3days.Checked—uponemonthaftertheoperation,AFPdecreasedtoregular
7、rangein34patientsandcompletetumornecrosiswasachievedinallthepatientsbyCTorU1一trasound.Duringfollow-upof5-22months,3patientshadnewmalignantnodulesforwhomLRFAwasperformedsuccessfullyagain.ConclusionsLRFAforspecialpartssmalllivercancerprov
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