脓毒症患者血NT-pro-BNP水平与APACHEⅡ评分相关性研究.pdf

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1、·临床研究·中国当代医药2014年8月第2l卷第24期脓毒症患者血NT—pro—BNP水平与APACHEII评分相关性研究‘赵林岩朱丹丹李芳于健1．大连医科大学附属第二医院重症医学科(ICU)，大连116027；2．大连市中心医院神经内科，大连116033【摘要】目的探讨脓毒症患者血N端前体脑钠肽(NT—pro—BNP)及APACHEII评分的相关性。方法选取本院连续收治的80例脓毒症患者作为研究对象，在24h内进行APACHE1I评分，并测定血浆NT—pro—BNP水平，比较不同APACHEII评分分值组血NT—pro—BNP水平。结果C组血NT—pro—

2、BNP水平明显高于B组，差异有统计学意义(P<0．05)：D组血NT—pro—BNP水平明显高于C组，差异有统计学意义(P

3、识码】A【文章编号】1674—4721(2014)08(c)一0070—03CorrelationstudyofNT—pro—BNPlevelandAPACHEⅡscoreinsepticpatientsZHA0Lin-yanlZHUDan—danlLIF叭YUJ／an1．IntensiveCareUnit，theSecondAffiliatedHospitalofDalianMedicalUniversity，Dalian116027，China；2．DepartmentofNeurology，CentralHospitalofDalianCity，Dal

4、ian116033，China[Abstract]ObjectiveTodiscussthecorrelationbetweenN—terminalprecursorofbrainnatriureticpeptidefNT—pro—BNP)andAPACHEIIscoreinsepticpatients．MethodsEightysepticpatientswereselectedinourhospitalasresearchobjects．TheAPACHEIIscorewasperformedinallselectedpatientswithin24ho

5、ursandthelevelofNT—pro-BNPfromplasmawastested．TheconcentrationofNT—pro—BNPindifferentAPACHEIIscoregroupswascompared．ResultsLevelofNT-pro—BNPingroupcwasobviouslyhigherthanthatingroupB．withstatisticaldifference(P<0．05)．ThelevelofNT-pro-BNPingroupDwasgreatlyhigherthanthatingroupC，with

6、statisticaldifference(P<0．01)．Therewasasig‘nificantcorrelati0nbetweenlevelofbloodNT—pro—BNPandAPACHEIIscorefr=0．682，P

7、ncentrationofbloodNT—pro—BNPgetsenrichedcorespond-ingly．ThereisapositivecorelationbetweenconcentrationofbloodNT—pro—BNPandAPACHEIIscore，whichisapreferableindexinclinicalevaluationofsepticpatientSprognosis．[Keywords]Sepsis；N-terminalprecursorofbraifinatriureticpeptide；APACHEⅡscore；C

8、orelation脓毒症是指因感染而导致的全身炎症反