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时间:2020-05-24
《甲状腺微小癌健康筛查的超声征象分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·1378·浙江临床医学2014年9月第16卷第9够甲状腺微小癌健康筛查的超声征象分析郑雅兰郑媛媛宋会明孙建明【摘要】目的探讨甲状腺微小癌健康筛查的超声征象。方法回顾胜分析86个甲状腺微小癌与84个≤lcm的甲状腺良性结节的灰阶超声表现,比较分析两组间结节的回声、形态、边界、纵横比、内部成分、声晕、微小钙化,比较各组间超声征象的敏感性、特异性、准确性。结果两组间极低回声、形态不规整、实性回声、纵横比≥1、不规则声晕、微小钙化差异有统计学意义。使用极低回声、纵横比≥1、微小钙化这三项特异性高的超声征象作为联合诊断指标,敏感性为88.4%,特异性为
2、76.2%,准确性为82.4%。结论极低回声、纵横比≥1、微小钙化三项超声指标联合运用,在健康体检中能快速、有效地筛查出甲状腺微小癌。【关键词】超声检查甲状腺微小癌健康【Abstract】ObjectiveToexplorertheultrasonicsignsofhealthscreeninginthediagonosisofthyroidmicrocarcinoma(TMC).MethodsThesonographiccharacetersof86TMCand84benignthyriodnodes(≤lcm)wereretrospecti
3、velyreviewedandcomparedwitheachother,incluededingechogenicity,shape,boundary,anteroposteriortotransversedimensionratio(A/T),internalcomponent,halosign,microcalcificationandSOon.Sensitivity,specificity,accuracyamongtheultrasonicsignswerecompared.ResultsThereweresignificantlys
4、tatisticaldiferencesbetweenthemalignantandbenignnodules,whichweremarkedhypoecho,irregularsharpe,solidlesion,A/T≥1,irregularhalosignandmicrocalcification.Whenusingmarkedinternalhypoechoicecho,A/T/>1andmicrocalcificaionasanewcombinedcriterior,thesensitivity,spicificityandaccur
5、acywere88.4%,76.2%and82.4%respectively.ConclusionsThecombinedcriteriorusingmarkedhypoechoicecho.A/T~>1andmicrocalcificaioncanrapidly,efectivelyscreeningtheTMCinhealthexamination.【Keywords】UltrasonographyThyroidnodulesHealth作者单位:312008浙江省绍兴市人民医院超声科为指导治疗和判断预后的核心[。研究证实,宫颈癌胞增殖活跃
6、发生侵袭转移有关。患者VEGF表达增强常有血管、淋巴结侵犯和肝脏等参考文献脏器转移,病情发展迅速、复发快、术后生存期短。而本资料结果显示VEGF阳性表达者有23.29l7/73)1JemalA,BrayF,CenterMM,eta1.Glob~cancerstatistics.CACancerJClin,2011,61(2):69~90.发生淋巴结转移,34.25%(25/73)发生脉管浸润,而2WeidnerN,FolkmanJ,PozzaF,eta1.Tumorangiogenesis:anew表达阴性者则淋巴结转移为0(0/22)和发生脉
7、管浸润significantandindependentprognosticindicatorinearly—stagebreast9.o9%(2/22),前后两者比较有显著性差异(P<0.05),carcinomaONatlCancerInst,1992,84:1875~1887与上述文献报道结果一致,故作者认为,将VEGF作3JohnstoneS,LoganRMTheroleofvascularendothelialgrowth为评价肿瘤进展和预后不良的判断指标之一具有一factoi(VEGF)inoraldysplasiaandorgls
8、quamouscellcarcinomaJOralOncol,2006,42(4):337—042.定可行性。4姜星,李敏,雷瑛,等.VEGF在子宫颈
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