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《酒精性肝硬化与乙型肝炎肝硬化、丙型肝炎肝硬化及自身免疫性肝硬化临床特点对比分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、传染病信息2013年10月3O日第26卷第5期InfectDisInfo,Vo1.26,No.5,October30,2013.279.酒精性肝硬化与乙型肝炎肝硬化、丙型肝炎肝硬化及自身免疫性肝硬化临床特点对比分析单晓辉,郝书理,孙颖,常彬霞,滕光菊,赵军,张伟,李保森,邹正升【摘要】目的探讨酒精性肝硬化的临床特点及其与乙型肝炎(乙肝)肝硬化、丙型肝炎(丙肝)肝硬化和自身免疫性肝硬化临床特点的异同。方法总结和分析2002-2012年住我院的部分酒精性肝硬化患者(373例)的临床特点,并与同期住院的部分乙肝肝硬化患者(205
2、例)、丙肝肝硬化患者(104例)和自身免疫性肝硬化患者(121例)的临床特点进行对比分析。结果酒精性肝硬化患者好发年龄段为4059岁(68.36%),尤其以4049岁发病率最高,达到43.43%。与其他3种病因所致的肝硬化患者相比,酒精性肝硬化患者男性占绝大多数(98.66%),差异有统计学意义(P3、IL和GGT/ALP比值均明显高于其他3种病因所致的肝硬化患者,差异有统计学意义(P均<0.01)。结论酒精性肝硬化在我国的发病率不断升高,且与乙肝肝硬化、丙肝肝硬化和自身免疫性肝硬化相比有其独特的临床特点。应对酒精性肝硬化给予更多关注。[关键词】肝硬化,酒精性;乙型肝炎;丙型肝炎;肝炎,自身免疫性;体征和症状[中国图书资料分类号】R575.2;R512.6[文献标志码】A『文章编号】1007—8134(2013)05—0279—05Comparativeanalysisofclinicalfeaturesofalcoho4、liccirrhosisandcirrhosisduetohepatitisB.hepatitisCandautoimmuneliverdiseasesSHANXiao—hui,HAOShu—li,SUNYing,CHANGBin—xia,TENGGuang-5u,ZHAOJun,ZHANGWei,LIBao-sen,ZOUZheng-shengDepartmentofInternalMedicine,theFirstHospitalofYongnianCounty,Yongnian,Hebei057150,ChinaCo5、rrespondingauthor.LIBao-sen,E-mail:libaosenl6@sina.com;ZOUZheng-sheng,E-mail:zszou302@163.corn[Abstract】ObjectiveToinvestigatetheclinicalfeaturesofalcoholiccirrhosisandcomparethemwiththoseofcirrhosisduetohepatitisB,hepatitisCandautoimmuneliverdiseases.MethodsThecl6、inicalfeaturesof373patientswithalcoholiccirhosisad—mittedtoourhospitalfrom2002to2012wereanalyzed,andcomparedwiththoseof205patientswithcirrhosisduetohepatitisB,104patientswithcirrhosisduetohepatitisCand121patientswithcirhosisduetoautoimmuneliverdiseasesadmittedinth7、esameperiod.ResultsAlcoholiccirrhosiswasmostlikelytooccurinthoseaged40—59withtheprevalenceof68.36%.especiallyinthoseaged40-49withthehighestprevalenceof43.43%.Ascomparedwithpatientswithcirhosisduetotheotherthreecauses.malesaccountedforthelargestproportioninpatients8、withalcoholiccirrhosis(98.66%)(P<0.01).ThelevelsofWBC,absoluteneu-trophilcount,neutrophil/lymphocyteratioandMCVinpatientswithalcoholiccirhosisweresignif
3、IL和GGT/ALP比值均明显高于其他3种病因所致的肝硬化患者,差异有统计学意义(P均<0.01)。结论酒精性肝硬化在我国的发病率不断升高,且与乙肝肝硬化、丙肝肝硬化和自身免疫性肝硬化相比有其独特的临床特点。应对酒精性肝硬化给予更多关注。[关键词】肝硬化,酒精性;乙型肝炎;丙型肝炎;肝炎,自身免疫性;体征和症状[中国图书资料分类号】R575.2;R512.6[文献标志码】A『文章编号】1007—8134(2013)05—0279—05Comparativeanalysisofclinicalfeaturesofalcoho
4、liccirrhosisandcirrhosisduetohepatitisB.hepatitisCandautoimmuneliverdiseasesSHANXiao—hui,HAOShu—li,SUNYing,CHANGBin—xia,TENGGuang-5u,ZHAOJun,ZHANGWei,LIBao-sen,ZOUZheng-shengDepartmentofInternalMedicine,theFirstHospitalofYongnianCounty,Yongnian,Hebei057150,ChinaCo
5、rrespondingauthor.LIBao-sen,E-mail:libaosenl6@sina.com;ZOUZheng-sheng,E-mail:zszou302@163.corn[Abstract】ObjectiveToinvestigatetheclinicalfeaturesofalcoholiccirrhosisandcomparethemwiththoseofcirrhosisduetohepatitisB,hepatitisCandautoimmuneliverdiseases.MethodsThecl
6、inicalfeaturesof373patientswithalcoholiccirhosisad—mittedtoourhospitalfrom2002to2012wereanalyzed,andcomparedwiththoseof205patientswithcirrhosisduetohepatitisB,104patientswithcirrhosisduetohepatitisCand121patientswithcirhosisduetoautoimmuneliverdiseasesadmittedinth
7、esameperiod.ResultsAlcoholiccirrhosiswasmostlikelytooccurinthoseaged40—59withtheprevalenceof68.36%.especiallyinthoseaged40-49withthehighestprevalenceof43.43%.Ascomparedwithpatientswithcirhosisduetotheotherthreecauses.malesaccountedforthelargestproportioninpatients
8、withalcoholiccirrhosis(98.66%)(P<0.01).ThelevelsofWBC,absoluteneu-trophilcount,neutrophil/lymphocyteratioandMCVinpatientswithalcoholiccirhosisweresignif
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