欢迎来到天天文库
浏览记录
ID:55578550
大小:392.51 KB
页数:5页
时间:2020-05-18
《围生期窒息新生儿有核红细胞计数与早期脑损伤的关系.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·5O·ChinJObstetGynecolPediatr(ElectronEd),February2015,Vo1.11,No.1·论著·围生期窒息新生儿有核红细胞计数与早期脑损伤的关系谭宁彭华保费淑兰王永红史文元陈磊【摘要】目的探讨有核红细胞(NRBC)计数与围生期窒息新生儿早期脑损伤的关系。方法选择2011年5月1日至2013年1O月1日在南华大学附属郴州市第一人民医院产科分娩的足月新生儿共计140例为研究对象,根据有无围生期窒息将其分为围生期窒息组(一55)及正常组(一85)。根据新生儿缺氧缺血性脑病(HIE)诊断标准,将围生期窒息组进一步分为4个亚组:重度脑病亚组(,
2、z一6)、中度脑病亚组(7l一7)、轻度脑病亚组(n一12)及无脑病亚组(一30)。采集新生儿脐动脉血及生后1~4d足跟末梢血,测定NRBC计数,并于随访至出生3个月时测定Gesell发育商。采用统计学方法比较各组及各亚组NRBC计数差异,并分析脐动脉血NRBC计数与Gesell发育商的相关性。围生期窒息组与正常组新生儿性别构成比、分娩方式构成比、出生体质量、胎龄及母亲年龄比较,差异均无统计学意义(P>0.05)。本研究遵循的程序符合南华大学附属郴州市第一人民医院人体试验委员会制定的伦理学标准,得到该委员会批准,分组征得受试对象监护人知情同意,并与监护人签署临床研究知情同意书。
3、结果①围生期窒息组患儿脐动脉血NRBC计数较正常组显著升高,而血气分析pH值则较正常组显著降低,且差异均有统计学意义(t一5.52,7.18;P4、常组)两两比较,均为脑病程度重亚组较程度轻亚组显著升高,且差异有统计学意义(P5、;幼红细胞;缺氧缺血,脑;婴儿,新生CorrelationbetweennucleatedredbloodcellcountandearlybraininjuryinperinataiasphyxianewbornsTanNing,PengHuabao,FeiShulan,WangYonhong,ShiWenyuan,ChenLei.DepartmentofNeonatology,FirstPeople5HospitalofChenzhou,SouthChinaUniversity,Chenzhou423000,HunanProvince,ChinaC0rrPsp0gautho6、r:PengHuabao,Email:by—phb@sina.corn[Abstract]ObjectiveToexplorethecorrelationbetweennucleatedredbloodcell(NRBC)countandearlybraininjuryinperinatalasphyxianewborns.MethodsAtotalof140full—termnewbornswhowereborninDepartmentofObstetrical,FirstPeopleSHospitalofChenzhou,SouthChinaUniversity,fromM7、ay1,2011tOOctoberl,2013werechosenasstudysubjects。Theyweredividedintoperinatalasphyxiagroup(一55)andnormalgroup(n=85)inaccordancewithwhetherhadperinatalasphyxia.Andalsoaccordingtoneonatalhypoxicischemicencepha1opathy(HIE)diagnosticcriteriaforjudgingw
4、常组)两两比较,均为脑病程度重亚组较程度轻亚组显著升高,且差异有统计学意义(P5、;幼红细胞;缺氧缺血,脑;婴儿,新生CorrelationbetweennucleatedredbloodcellcountandearlybraininjuryinperinataiasphyxianewbornsTanNing,PengHuabao,FeiShulan,WangYonhong,ShiWenyuan,ChenLei.DepartmentofNeonatology,FirstPeople5HospitalofChenzhou,SouthChinaUniversity,Chenzhou423000,HunanProvince,ChinaC0rrPsp0gautho6、r:PengHuabao,Email:by—phb@sina.corn[Abstract]ObjectiveToexplorethecorrelationbetweennucleatedredbloodcell(NRBC)countandearlybraininjuryinperinatalasphyxianewborns.MethodsAtotalof140full—termnewbornswhowereborninDepartmentofObstetrical,FirstPeopleSHospitalofChenzhou,SouthChinaUniversity,fromM7、ay1,2011tOOctoberl,2013werechosenasstudysubjects。Theyweredividedintoperinatalasphyxiagroup(一55)andnormalgroup(n=85)inaccordancewithwhetherhadperinatalasphyxia.Andalsoaccordingtoneonatalhypoxicischemicencepha1opathy(HIE)diagnosticcriteriaforjudgingw
5、;幼红细胞;缺氧缺血,脑;婴儿,新生CorrelationbetweennucleatedredbloodcellcountandearlybraininjuryinperinataiasphyxianewbornsTanNing,PengHuabao,FeiShulan,WangYonhong,ShiWenyuan,ChenLei.DepartmentofNeonatology,FirstPeople5HospitalofChenzhou,SouthChinaUniversity,Chenzhou423000,HunanProvince,ChinaC0rrPsp0gautho
6、r:PengHuabao,Email:by—phb@sina.corn[Abstract]ObjectiveToexplorethecorrelationbetweennucleatedredbloodcell(NRBC)countandearlybraininjuryinperinatalasphyxianewborns.MethodsAtotalof140full—termnewbornswhowereborninDepartmentofObstetrical,FirstPeopleSHospitalofChenzhou,SouthChinaUniversity,fromM
7、ay1,2011tOOctoberl,2013werechosenasstudysubjects。Theyweredividedintoperinatalasphyxiagroup(一55)andnormalgroup(n=85)inaccordancewithwhetherhadperinatalasphyxia.Andalsoaccordingtoneonatalhypoxicischemicencepha1opathy(HIE)diagnosticcriteriaforjudgingw
此文档下载收益归作者所有