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时间:2020-05-15
《妊娠20周前甲状腺功能异常对妊娠的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、蕾堇;}当代医学2015年2月第21卷第6期总第377期ContemporaryMedicine,Feb.2015,Vo1.21No.6IssueNo.377doi:10.3969/j.issn.1009-4393.2015.6.033妊娠20周前甲状腺功能异常对妊娠的影响陈小丽阳成英杨武黄风英【摘要]目的探讨妊娠2O周前甲状腺功能异常对妊娠结局的影响。方法选择产检的176例甲状腺功能异常孕妇作为观察组,并将同期的176例甲状腺功能正常孕妇作为对照组,观察2组的妊娠结局和孕期合并疾病状况。结果观察组发生早产、流产、低出生体重儿和胎儿窘迫的发生率均高于
2、对照组,除胎儿窘迫外,2组间的差异均有统计学意义(均P<005)。其中观察组早产、流产、低出生体重儿和胎儿窘迫发生率分别为511%、511%、568%和227%,对照组分别为114%、1.14%、170%和1.14%。观察组妊娠期合并高血压、糖尿病和贫血发生率分别为1477%、15.91%和966%,对照组分别为966%、5】1%和3.98%,2组比较差异有统计学意义(=4873,p=O027,=10903,P=OO01;4472,p=o054)。结论妊娠2o周前甲状腺功能异常可增加妊娠并发症的发生率,增加不良妊娠结局。[关键词】甲状腺功能异常;妊娠
3、结局;20周;胎儿窘迫[Abstract】0bjectiveToinvestigateefectsofthyroiddysfunctiononpregnancyoutcomeon20gestationalweeksago.Methods176casesofthyroiddysfunctionofprenatalpregnantwomenwereasobservationgroup,andinthesameperiod176casesofnormalthyroidfunctionofpregnantwomenwereascontrolgroup,pre
4、gnancyoutcomeandthepregnancymergediseaseconditionoftwogroupswereobserved.ResultsTheprematurebinh,abortion,lowbirthweightandtheincidenceoffetaldistressinobservationgroupwerehigherthanthoseincontrolgroup,thefetaldistress,thediferencesbetweenthetwogroupshadstatisticalsignificance(
5、0.05).111eobservationgroupofprematurebirth,abo~ion,lowbirthweightandtheincidenceoffetaldistresswere5.11%,5.11%,5.68%and5.11%respectively,thecontrolgroupwas1.14%,1.14%,1.70%and1.14%.Thepregnancymergetheproportionofhighbloodpressure,diabetesandanemiainobservationgroupwerehigherth
6、anthoseinthecontrolgroup,andthediferencesbetweenthetwOgroupshadstatisticalsignificance(P<0.05).Theobservationgroupofgestationalhypertension,diabetes,andincidenceofanemiawas14.77%,l5.91%and9.66%,controlgroupwere9.66%,5.11%and3.98%(=4.873,尸=O.027,=10.903,P=0.001;;4.472,P=0.034).C
7、onclusionThyroiddysfimction20gestationalweeksagocanincreasetheincidenceofpregnancycomplications,increasetheadversepregnancyoutcomes.【Keywords】Thyroiddysfunction;Pregnancyoutcomes;20weeks;Fetaldistress近年来,随着人们生活水平的提高,饮食结构的改变以及产1.3统计学方法本次实验数据采用SPSS19.0软件进前检查越来越系统化、正规化,妊娠20周前甲状腺功能
8、异常的检行统计学分析,其中正态计量资料对比采用t检验,计数资料对出率呈现出逐年上升趋势⋯。孕期妊娠20周前甲
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