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时间:2020-05-14
《淋巴细胞比值与急性缺血性脑梗塞预后的关系.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、,r。‘C鹱Iin与P病at理h0杂l志Res2014,34(、5)http:⋯//w⋯w⋯一lcb⋯l-⋯netDOI:IO.11714/j.issn.2095—6959.2014.05.012http://www.1cb1.net/articles/642中性粒细胞/淋巴细胞比值与急性缺血性脑梗塞预后的关系高巍,韩志君,杜永胜,王栩彬,张勇(1.无锡新区凤凰医院内科,江苏无锡241002;2.无锡市第二人民医院检验科,江苏无锡214000;3.安徽省合肥第二人民医院内科,合肥230010)【摘要】目的:研究中性粒细胞/淋巴细胞比值(neutrophillymphocyt
2、eratio,NLR)与急性缺血性脑梗塞(acuteischemicstroke,AIS)预后的关系。方法:回顾性地分析了6O例AIS病患者和61例健康个体白细胞(whitebloodcell,WBC)计数、淋巴细胞计数、中性粒细胞计数和NLR检测结果。用Spearman法分析这些指标与患者出院时的改良Rankin评分(modifiedRankinscale,mRS)之间的关系。结果:AIS患者WBC计数、中性粒细胞计数和NLR均较健康个体增高(P均小于0.01),淋巴细胞计数则降低(P3、NLR是预~lhas患者预后的有益指标,其与疾病预后的关系较WBC计数、中性粒细胞计数和淋巴细胞计数更为密切。【关键词】急性缺血性脑梗塞;中性粒细胞;淋巴细胞;中性粒细胞和淋巴细胞比值;改良Rankin评分Associationbetweenneutrophillymphocyteratioandpro】21nOSI●SOl-acut.e_●sch■em_●Cst·rok●eGAOWeiJHANZhijunJDUYongshengJWANGXubinJZHANGYongDepartmentofMedicine,WuxiNewDistrictPhoenixHospital,W4、uxi]iangsu241002i2.DepartmentClinicalLaboratory,WuxiNo.2People'sHospital,Wuxi]iangsu21400~3.DepartmentofMedicine,AnhuiNo.2ProvincePeople'sHospital,Hefei230010,China)AbstractObjective:Toinvestigatethecorrelationbetweenneutrophillymphocyteratio(NLR)andprognosisofacuteischemicstroke(has).Meth5、ods:TheroutinelaboratoryhematologytestsJincludingwhitebloodcell(WBC)count,neutrophil,lymphocyteandNLRJof60MSpatientsand61healthyindividualswereretropectivelyreviewed.TheassociationbetweenthesetestsandmodifiedRankinscale(mRS)wasanalyzedbySpearmanapproach.Results:IncreasedWBneutrophilandNLR(6、a1lPvalues7、chemicstroke;neutrophil;lymphocyte;neutrophillymphocyteratio;modifiedrankinscale收稿日期(Dateofreception):2014—08—05通信作者(Correspondingauthor):高巍,Emaihwxgw225@163.corn临床与病理杂志,2014,34(5)http://www.1cb1.net缺血性脑梗塞(acuteischemicstroke,AIS)是1.2患者临床特征的获取一种发病率和致残率均较高的疾病,是
3、NLR是预~lhas患者预后的有益指标,其与疾病预后的关系较WBC计数、中性粒细胞计数和淋巴细胞计数更为密切。【关键词】急性缺血性脑梗塞;中性粒细胞;淋巴细胞;中性粒细胞和淋巴细胞比值;改良Rankin评分Associationbetweenneutrophillymphocyteratioandpro】21nOSI●SOl-acut.e_●sch■em_●Cst·rok●eGAOWeiJHANZhijunJDUYongshengJWANGXubinJZHANGYongDepartmentofMedicine,WuxiNewDistrictPhoenixHospital,W
4、uxi]iangsu241002i2.DepartmentClinicalLaboratory,WuxiNo.2People'sHospital,Wuxi]iangsu21400~3.DepartmentofMedicine,AnhuiNo.2ProvincePeople'sHospital,Hefei230010,China)AbstractObjective:Toinvestigatethecorrelationbetweenneutrophillymphocyteratio(NLR)andprognosisofacuteischemicstroke(has).Meth
5、ods:TheroutinelaboratoryhematologytestsJincludingwhitebloodcell(WBC)count,neutrophil,lymphocyteandNLRJof60MSpatientsand61healthyindividualswereretropectivelyreviewed.TheassociationbetweenthesetestsandmodifiedRankinscale(mRS)wasanalyzedbySpearmanapproach.Results:IncreasedWBneutrophilandNLR(
6、a1lPvalues7、chemicstroke;neutrophil;lymphocyte;neutrophillymphocyteratio;modifiedrankinscale收稿日期(Dateofreception):2014—08—05通信作者(Correspondingauthor):高巍,Emaihwxgw225@163.corn临床与病理杂志,2014,34(5)http://www.1cb1.net缺血性脑梗塞(acuteischemicstroke,AIS)是1.2患者临床特征的获取一种发病率和致残率均较高的疾病,是
7、chemicstroke;neutrophil;lymphocyte;neutrophillymphocyteratio;modifiedrankinscale收稿日期(Dateofreception):2014—08—05通信作者(Correspondingauthor):高巍,Emaihwxgw225@163.corn临床与病理杂志,2014,34(5)http://www.1cb1.net缺血性脑梗塞(acuteischemicstroke,AIS)是1.2患者临床特征的获取一种发病率和致残率均较高的疾病,是
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