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时间:2020-05-14
《联合检测抗磷脂抗体、血β-HCG、血钙、平均动脉压预测妊高征的临床价值.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·临床研究·2011年8月第8卷第24期联合检测抗磷脂抗体、血13-HCG、血钙、平均动脉压预测妊高征的临床价值王亚华,张永风1.广东省汕头市潮南民生医院妇产科,广东汕头515144;2.汕头大学第一附属医院妇产科,广东汕头515001【摘要】目的:检测孕中期孕妇血清抗心磷脂抗体、血钙与血13一HCG的水平,探讨联合监测孕妇平均动脉压对妊娠高血压综合征(妊高征)发生的预测价值,寻求一种简便、实用、易行的预测方法。方法:对180例妊娠l6~20周的孕妇进行前瞻性研究,测定其血抗心磷脂抗体(ACA)、血钙水平及血8一HCG值,同时监测平均动脉压,并观察发展为程度不同妊高征时
2、上述指标的变化规律。结果:妊高征孕妇在孕中期血13一HCG值、ACA阳性率、平均动脉压≥85nlnlHg的发生率均较正常组明显升高,差异有统计学意义(P3、011)08(c)一034-03.Thesignificance0fanticardi0lipinantibodies,[3-HCG,serumcalcium,meanarterialbloodpressureinearlypregnancyinpredictionofpregnancy-in—ducedhypertensionWANGYahud,ZHANGYonn1.DepartmentofGynaecologyandObstetrics,ChaonanMinshengHospitalofShantouCity,GuangdongProvince,Shantou5154、14,China;2.DepartmentofGynaecologyandObstetrics,theFirstAfiliatedHosptialofShantouUniversity,Guang-dongProvince,Shantou515001,China[Abstract]Objective:Toinvestigatethepredictingvalueofpregnancyinducedhypertension(PIH)bymeasuringthelevel·ofbloodanticardiolipinantibodies(ACA),p—HCGinblood,5、bloodcalcium,andtllemeanarterialbloodpressure(mABP),tofindasimple,easyandclinicalvalueofforecastingmethods.Methods:TheprospectivestudiesWasabout180Casr~ofpregnantwomen(16-20gestationalweeks)whosebloodweredrewtomeasureACA,13-HCG,bloodcalciumandmeanmABP,andtheabove-mentionedindexesinvariou6、sdegreePIHpatientswereobserved.Results:Blood13-HCClevels,A—CA-positive,theoccurrenceofMAP>185mmHgweresignificantlyhigherinpregnancieswholaterdevelopedPIHthanthoseinnormalpregnancies(P<0.05),blodcalciumlevelsweresignificantlylower(P≮O.05).Predictorofthefourindexscombined,thepositivepredic7、tivevaluewas80.95%,negativepredictivevaluewas98.74%,sensitivityWas89.47%andspecificityof97.52%.Conclusion:Thecombineddetectionofmid-pregnancybloodACA,blood13-HCG,bloodcalcium,mABPcanforecastPIH,anditisbetterthananysingleforecastingindex.[Keywords]Anticardiolipinantibodies
3、011)08(c)一034-03.Thesignificance0fanticardi0lipinantibodies,[3-HCG,serumcalcium,meanarterialbloodpressureinearlypregnancyinpredictionofpregnancy-in—ducedhypertensionWANGYahud,ZHANGYonn1.DepartmentofGynaecologyandObstetrics,ChaonanMinshengHospitalofShantouCity,GuangdongProvince,Shantou515
4、14,China;2.DepartmentofGynaecologyandObstetrics,theFirstAfiliatedHosptialofShantouUniversity,Guang-dongProvince,Shantou515001,China[Abstract]Objective:Toinvestigatethepredictingvalueofpregnancyinducedhypertension(PIH)bymeasuringthelevel·ofbloodanticardiolipinantibodies(ACA),p—HCGinblood,
5、bloodcalcium,andtllemeanarterialbloodpressure(mABP),tofindasimple,easyandclinicalvalueofforecastingmethods.Methods:TheprospectivestudiesWasabout180Casr~ofpregnantwomen(16-20gestationalweeks)whosebloodweredrewtomeasureACA,13-HCG,bloodcalciumandmeanmABP,andtheabove-mentionedindexesinvariou
6、sdegreePIHpatientswereobserved.Results:Blood13-HCClevels,A—CA-positive,theoccurrenceofMAP>185mmHgweresignificantlyhigherinpregnancieswholaterdevelopedPIHthanthoseinnormalpregnancies(P<0.05),blodcalciumlevelsweresignificantlylower(P≮O.05).Predictorofthefourindexscombined,thepositivepredic
7、tivevaluewas80.95%,negativepredictivevaluewas98.74%,sensitivityWas89.47%andspecificityof97.52%.Conclusion:Thecombineddetectionofmid-pregnancybloodACA,blood13-HCG,bloodcalcium,mABPcanforecastPIH,anditisbetterthananysingleforecastingindex.[Keywords]Anticardiolipinantibodies
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