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时间:2020-05-14
《连花清瘟颗粒联合利巴韦林和康复新液治疗疱疹性口腔炎的疗效观察.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·42·金堡药年2月第8卷第2期中ChinJofClinicalRationalDmgUse.Febmary2015.Vo1.8N0.2B·论著·连花清瘟颗粒联合利巴韦林和康复新液治疗疱疹性口腔炎的疗效观察李小莉【摘要】目的观察连花清瘟颗粒联合利巴韦林和康复新液治疗疱疹性口腔炎的临床疗效。方法选择2012年1—1O月份在医院儿科门诊进行诊治的疱疹性口腔炎的患儿80例,完全随机平分为治疗组和对照组各40例,2组除给予维生素C和维生素B等支持、对症治疗以外,均给予利巴韦林注射液静脉滴注10~15mg·kg·d,分2次给药和口服康复新液
2、,<3岁患儿每次5ml,>3岁患儿每次10ml,均3次/d,治疗组患儿在此治疗基础上加用连花清瘟颗粒口服(石家庄以岭药业股份有限公司,6袋),≤3岁3g/次,3R/d;>3岁6次,3次/d,均治疗5d。结果治疗组总有效率为97.5%明显高于对照组的87.5%(P<0.01),治疗组热退时间,口腔炎疱疹溃疡愈合时间为(1.4±0.7)d、(2.9±0.6)d比较对照组的(3.2±1.2)d、(3.7±0.9)d明显缩短,差异有统计学意义(P<0.01)。结论连花清瘟颗粒联合利巴韦林和康复新液治疗疱疹性口腔炎,能迅速缓解临床症状,疗效
3、确切,值得临床推广和应用。【关键词】连花清瘟;利巴韦林;康复新液;疱疹性口腔炎;临床疗效【中图分类号】R781【文献标识码】A【文章编号】1674—3296(2015)02B一0042—02doi:10.15887/j.cnki.13-1389/r.2015.05.020ObservationofcurativeefectofLianhuaqingwenparticlescombinedwithribavirinandKangfuxinyeinthetreatmentofherpeticstomatitisL/Xiao—li.De
4、partmentofPediatrics,theSecondHospitalofXian,Shanxi710003,China【Abstract】ObjectiveToobservetheclinicaleficacyofLianhuaqingwenparticlescombinedwithribavirinandKangfuxinyefluidintreatmentofherpeticstomatitis.Methods80casesofchildrenwithherpeticstomatitisinoutpatientde—p
5、arlmentofPediatricsofourhospitalwererandomlydividedequallyintotreatmentgroupandcontrolgroup,eachof40cases.InadditiontogivingvitaminCandvitaminB2andothersupport,symptomatictherapy,bothgroupsweregivenribavirinintrave—DOHSinjection10~15mg·kg一·d),in2divideddosesandoralKan
6、gfuxinyeunder3yearsoldper5ml,3yearsoldper10mlwere3timesaday.ThetreatmentgroupbasedontheuseofthistreatmentweregivenLianhuaqingwenoralgranules(Shi—jiazhuangYilingPharmaceuticalCo.,Ltd.,6g/bags),≤3yearsper3g,3timesaday;>3agedper6g,3timesaday.Bothgroupsweretreatedfor5days
7、.ResultsThetotaleffectiveratewas97.5%inthetreatmentgroup.whichwashigherthan87.5%ofthecontrolgroup,andthedifferencewasstatisticallysignificant(P<0.01);theheatbacktime,stomatitisherpessoreshealingtimeofthetreatmentgroupwassignificantlyshoflerthanthecontrolgroup[(1.4±0.7
8、)dratio(3.2±1.2)d,(2.9±0.6)dratio(3.7±0.9)d,bothP<0.01],andthedifferencewasstatisticallysignificant(P<0.01).ConclusionLianhu
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