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《口腔健康教育对维持性血液透析患者微炎症状态的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·203·中国血液净化2015~V4月第14卷第4期ChinJBloodPurif,ADri1,2015,Vo1.4,No.14·临床研究·口腔健康教育对维持性血液透析患者微炎症状态的影Ⅱ向钱芳刘同强丁钟琴【摘要】目的探讨口腔健康教育对维持性血液透析患者微炎症的影响。方法8O例患者随机分为治疗组40例,对照组40例,治疗组行口腔健康教育3个月,对照组未行口腔健康教育。观察两组患者口腔健康状况和微炎症状态的变化。结果治疗组经口腔健康教育3个月后牙龈出血指数(SBI)、菌斑指数(PLI)、牙龈指数(GI)和血清中肿瘤坏死因子a(TNF—d)、高敏c反应蛋白(
2、hs-CRP)水平均较干预前低[SBI,2.35±0.88比2.83±0.71(t=-2.684,P=O.009):PLI,1.63±0.46比1.994-0.51(t=3.323,P=O.001);GI,1.49±0.39比1.88±0.41(t=3.289,P:-0.002);TNF—Q,5.72±1.68ng/L比6.60±2.01ng/L(t=2.123,P=0.037):hs—CRP,30.36±9.25mg/L比38.12±12.59mg/L(t=3.141,P=0.002)],而对照组患者SBI、PLI、GI的指数和TNF—d、hsCRP水
3、平的干预前后的比较无差别(尸>0.05)。结论口腔健康教育可改善维持性血液透析患者微炎症状态,应重视对维持性血液透析患者口腔健康教育。【关键词】口腔健康教育;维持性血液透析;微炎症中图分类号:R318.16文献标识码:Adoi:10.3969/j,issn1671—4091.2015.04.004EffectoforaIhealtheducationoilmicro。inflammatorystateinmaintenancehemodialysispatientsQIANFang,LIUTong-qiang,D1NGZhong-qin.Hemodial
4、ysisCenter,theSecondChangzhouHospitalAt'-filiatedtoNanjingMedicalCollege,Changzhou213003,ChinaCorrespondingauthor."LIUTong-qiang,Email:fiuyt7106@126.com[Abstract]ObjectiveToexploretheefectoforalhealtheducationonmicro—inflammatorystateinmain—tenancehemodialysis(MHD)patients.Method
5、sEightypatientswererandomlydividedintothetreatmentgroup(n=40)orthecontrolgroup(n=40).Oralhealtheducationwascarriedonfor3monthsinpatientsinthetreatmentgroupbutnotinthoseinthecontrolgroup.Oralhealthconditionandmicro—inflammatorystatewerethenobservedinthetwogroupsofMHDpatients.Resul
6、tsGingivalbleedingindex(SBI),plaquein—dex(PLI),gingivalindex(GI),andsernmTNF一【Iandhs—CRPdecreasedinthetreatmentgroupafteroralhealtheducationfor3monthsf2.35+0.88vs.2.83~0.71,t=-2.684,P=-0.009forSBI;1.63+0.46vs.1.99+0.51.t=3.323,P一0.001forPLI;1.49i0.39vs.1.88~0.41,t=-3.289。P=0.002f
7、orGI;5.72:51.68ng/Lvs.6.60~2.01ng/L,t=-2.123,P=0.037forTNF一Ⅱ;30.36+9.25mg/Lvs.38.12+12.59mg/L,t=-3.141,0.002forhs—CRP).Theseindiceswereunchangedinthecontrolgroupf.P>0.05).conclusionOralhealtheducationcouldalle—viatemicro—inflammatorystateinMHDpatients.Therefore,oralhealtheducatio
8、nshouldbeconsideredasallimportantmeasure
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