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时间:2020-05-09
《超声弹性成像对乳腺肿块良恶性的鉴别诊断价值.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、第44卷第1期第114页华中科技大学学报(医学版)V0I.44NO.1P.1142O15年2月ActaMedUnivSciTechnolHuazhongFeb.2015超声弹性成像对乳腺肿块良恶性的鉴别诊断价值吴梓芳,陈天亮武汉大学医院超声诊断科,武汉430072山东省济宁医学院附属医院超声诊断科,济宁272000摘要:目的评价超声弹性成像(ultrasoundelastography,UE)对乳腺肿块良恶性的鉴别诊断价值。方法收集180例患有乳腺实性肿块女性患者的临床资料,对180个乳腺实性肿块分别进行术前常规超声(ultrasound,US)和UE检查,对肿块的
2、良恶性进行初步判断,以手术后组织病理结果作为标准,比较两种诊断方法的诊断符合率和ROC曲线特征值。结果UE正确诊断出48例良性和127例恶性肿块,US正确诊断出38例良性和J12例恶性肿块,UE对乳腺肿块良恶性诊断的灵敏度、特异度、准确度、阳性预测值与阴性预测值均高于US,差异具有统计学意义(均P<0.oa);UE组的ROC曲线下面积AUC值为0.926,高于常规超声组的AUC值0.899,差异有统计学意义(Z一2.8,P<0.05)。结论UE在乳腺肿块良恶性的鉴别诊断中具有高灵敏度、特异度和准确度等特点,应用价值高,但尚存在一定缺陷,在应用UE诊断乳腺疾病时,应结
3、合US综合评判。关键词:超声弹性成像;常规超声;乳腺肿块;鉴别诊断中图分类号:R730.4DOI:10.3870/j.issn.1672—0741.2015.01.023UltrasoundElastographyintheDifferentialDiagnosisofBenignandMalignantBreastLesionsWuZifang.ChenTianliangDepartmentofMedicalUltrasound,HospitalofWuhanUniversity,Wuhan430072,China。DepartmentofMedicalUltra
4、sound,AffiliatedHospitalofJiningMedicalUniversity0_,、ShandongProvince,Jining272000,ChinaAbstractObjectiveToassessthevalueofultrasoundelastography(UE)inthedifferentia1diagnosisofbenignandma—lignantbreastmasses.MethodsClinicaldataof180femalepatientswithbreastmasseswerecollected.Atotalof1
5、8Omassesinthesepatientsweredetectedbyultrasound(US)andUEtOprimarilyidentifythebenignormalignantmassesbeforesurgery.ThediagnosticcoincidencerateandvaluesofR0Ccurvewerecomparedbasedonthepostoperativepathologicresultsbetweenthetwodiagnosismethods.ResultsForty-eightbenignmassesand127malign
6、antmasseswerecorrectlydiagnosedbyUE,and38benignmassesand112malignantmassesbyUS.Thesensitivity,specificity,accuracy,positivepredictivevalueandnegativepredictivevaluewerehigherinUEgroupthaninUSgroup,andthereweresignificantstatistica1differences(P7、dertheROCcurve(AUC)inUEgroupwas0.926,significantlyhigherthanthatinUSgroup(O.899)(Z一2.8,P%0.05).ConclusionUEhastheadvantagesofhighsensitivity,specificityandaccuracyindifferentialdiagnosisofthenatureofbreastmasses.IntermsofsomedisadvadtagesofUE,UEshouldbe,combinedwithUSinthediagnosisof
7、dertheROCcurve(AUC)inUEgroupwas0.926,significantlyhigherthanthatinUSgroup(O.899)(Z一2.8,P%0.05).ConclusionUEhastheadvantagesofhighsensitivity,specificityandaccuracyindifferentialdiagnosisofthenatureofbreastmasses.IntermsofsomedisadvadtagesofUE,UEshouldbe,combinedwithUSinthediagnosisof
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