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《射频消融治疗合并重度肝硬化的小肝癌疗效分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、济宁医学院学报2014年4月第37卷第2期97doi:10.3969/j.issn.1000—9760.2014.02.007射频消融治疗合并重度肝硬化的小肝癌疗效分析钱瑞坤。乔森。刘建刚(山东省医学科学院,山东济南250062;济南大学山东省医学科学院医学与生命科学学院,济南2500623济宁医学院附属济宁市第~人民医院,山东济宁272011;济宁医学院临床学院,济宁272067)摘要目的评估射频消融术治疗合并重度肝硬化的小肝癌临床应用价值。方法连续收集合并重度肝硬化的小肝癌患者64例,根据治疗方式不同分为射频消融组和手术切除组。回顾性分析比较两组
2、患者的临床疗效及术后并发症、复发转移率。结果两组之间年龄、性别、术前肝功能分级、1a后肿瘤复发转移率和生存率比较,无显著性差异(PI,O.05)。射频消融组手术时间、术中出血量、术后镇痛剂使用例数,住院时间均明显低于肝癌切除组(P3、iceffectoftheradiofrequencyablationfortreatmentofhepatocellularcarcinomawithseverecirrhosisQIANRui—kun,QIAOSen,LjUJian—gang(ShandongAcademyofMedicalSciences,Jinan250260,China)Abstract:Objective64smalllivercancerpatientswithseverecirrhosisweredividedintotwogroups:thera—diofreque4、ncyablationgroupandcancerresectiongroup.Retrospectiveanalysisandcomparisonwerecarriedoutbe·tweenthetwogroupsofpatientswithclinicalefficacy,postoperativecomplicationsandrecurrencemetastasisrate.ResultsAge,gender,liverfunctionclassificationbeforeoperation,tumorrecurrenceandmetast5、asisrateandsur—vivalrateafter1yearsweresimilarinthetwogroups(P>O.05).Intheradiofrequencyablationgroup,operationtime,intraoperativebleeding,casesofusingpostoperativeanalgesic,hospitalstayweresignificantlylowerthanthoseofthecancerresectiongroup(P%0.05).Complicationssuchaspostoper6、ativebleeding,refractoryascites,liv—erfailurerateincancerresectiongroupweresignificantlyhigherthanthoseoftheradiofrequencyablationgroup(P<0.05).Conclusionl'hecurativeeffectofradi0frequencyablationintreatingsmalllivercancerpatientswithseverecirrhosisissimilartosurgicalresection,7、andhasfewercomplications.Keywords:Radi0frequencyablation;Smalllivercancer;Cirrhosisoftheliver肝癌是中国最常见的恶性肿瘤之一,手术切除1资料与方法被认为是肝癌治疗的首选厅式。肝功能差、凝血机制欠佳等原因导致手术切除后易出现多种并发症。1.1一般资料近年来,微创技术的迅猛发展,使射频消融术(ra—回顾性分析济宁医学院附属济宁市第一人民diofrequeneyablation,RFA)越来越受到术者的青医院2010年至2013年合并重度肝硬化的小肝癌睐,因其创伤小8、、并发症少、恢复快等优点成为治疗患者64例,所有的入组患者术前均行强化CT、合并有肝硬化、手术风险较大的小肝
3、iceffectoftheradiofrequencyablationfortreatmentofhepatocellularcarcinomawithseverecirrhosisQIANRui—kun,QIAOSen,LjUJian—gang(ShandongAcademyofMedicalSciences,Jinan250260,China)Abstract:Objective64smalllivercancerpatientswithseverecirrhosisweredividedintotwogroups:thera—diofreque
4、ncyablationgroupandcancerresectiongroup.Retrospectiveanalysisandcomparisonwerecarriedoutbe·tweenthetwogroupsofpatientswithclinicalefficacy,postoperativecomplicationsandrecurrencemetastasisrate.ResultsAge,gender,liverfunctionclassificationbeforeoperation,tumorrecurrenceandmetast
5、asisrateandsur—vivalrateafter1yearsweresimilarinthetwogroups(P>O.05).Intheradiofrequencyablationgroup,operationtime,intraoperativebleeding,casesofusingpostoperativeanalgesic,hospitalstayweresignificantlylowerthanthoseofthecancerresectiongroup(P%0.05).Complicationssuchaspostoper
6、ativebleeding,refractoryascites,liv—erfailurerateincancerresectiongroupweresignificantlyhigherthanthoseoftheradiofrequencyablationgroup(P<0.05).Conclusionl'hecurativeeffectofradi0frequencyablationintreatingsmalllivercancerpatientswithseverecirrhosisissimilartosurgicalresection,
7、andhasfewercomplications.Keywords:Radi0frequencyablation;Smalllivercancer;Cirrhosisoftheliver肝癌是中国最常见的恶性肿瘤之一,手术切除1资料与方法被认为是肝癌治疗的首选厅式。肝功能差、凝血机制欠佳等原因导致手术切除后易出现多种并发症。1.1一般资料近年来,微创技术的迅猛发展,使射频消融术(ra—回顾性分析济宁医学院附属济宁市第一人民diofrequeneyablation,RFA)越来越受到术者的青医院2010年至2013年合并重度肝硬化的小肝癌睐,因其创伤小
8、、并发症少、恢复快等优点成为治疗患者64例,所有的入组患者术前均行强化CT、合并有肝硬化、手术风险较大的小肝
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