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时间:2020-05-07
《低分子肝素钙治疗不稳定型心绞痛的效果观察-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·药物与临床·中国当代医药2014年2月第21卷第6期低分子肝素钙治疗不稳定型心绞痛的效果观察高静济南市第四人民医院护理部,济南250031【摘要】目的探讨低分子肝素钙治疗不稳定型心绞痛的临床效果。方法将诊断明确的不稳定型心绞痛患者80例,随机分为两组,每组40例,对照组采用常规治疗,观察组在对照组基础上,采用低分子肝素钙治疗,比较两组的疗效、疼痛减轻时间、疼痛消失时间、ST段下移幅度和T波倒置幅度。结果观察组的总有效率高于对照组,差异有统计学意义(P2、移及T波倒置均回升,观察组明显优于对照组,差异有统计学意义(P3、eopleSHospitalofJinanCity,Jinan250031,China【Abstract】0bjectiveTodiscussclinicaleffectoflowmolecularheparincalciuminthetreatmentofunstableanginapeetoris.Methods80patientswithdefinitediagnosisofunstableanginapectoriswererandomlydividedintotwogroups.eachgroupof40cases.Conventionaltreatme4、ntwasusedincontrolgroup,onthebasisofcontrolgroup,lowmolecularheparincalciumwasusedinobservationgroup.Effect,painrelieftime,paindisappeartime,STsegmentdownrangeandTwaveinversionrangewascomparedintwogoupsrespectively.ResultsTotaleffectiverateinobservationgroupwashigherthanthatincontrolg5、roup,withstatisticaldifference(P<0.05).Painrelieftimeandpaindisappeartimeinobserva—tiongroupwasshorterthanthatincontrolgrouprespectively.Aftertreatment,STsegmentdownandTwaveinversionwasrecoveredrespectively,observationgroupwasbetterthancontrolgroup,withstatisticaldifference(P<0.05).Co6、nclu—sionLowmolecularheparincalciuminthetreatmentofunstableanginapectoriscanobtaingoodeffectandhighersafety,noobviousadversereaction,whichisworthyofexpansionandapplicationinclinic.【Keywords】Lowmolecularheparincalcium;Unstableanginapectoris;Efectobservation不稳定型心绞痛(unstableanginapectori7、s.UAP)1.2治疗方法是急性冠脉综合征的一种,介于稳定型心绞痛和急两组均给予硝酸酯类药物为基础治疗,根据病情性心肌梗死之间,如果处理不及时.易发展为急性心变化给予B一受体阻滞剂、肠溶阿司匹林、钙通道阻滞肌梗死。本文旨在探讨低分子肝素钙治疗UAP的效剂等。两组的药物使用剂量及时间无明显差异。观察果。组在上述治疗基础上加用低分子肝素钙(河北唐山生1资料与方法化药业股份有限公司,生产批号130801)0.4ml皮下1.1一般资料注射,2次/d,疗程为7d。用药前排除对肝素过敏、6选择本科2012年5月~2013年5月收治的UAP个月内有外伤或大手术史、脑出血、严重凝8、血障碍疾患
2、移及T波倒置均回升,观察组明显优于对照组,差异有统计学意义(P3、eopleSHospitalofJinanCity,Jinan250031,China【Abstract】0bjectiveTodiscussclinicaleffectoflowmolecularheparincalciuminthetreatmentofunstableanginapeetoris.Methods80patientswithdefinitediagnosisofunstableanginapectoriswererandomlydividedintotwogroups.eachgroupof40cases.Conventionaltreatme4、ntwasusedincontrolgroup,onthebasisofcontrolgroup,lowmolecularheparincalciumwasusedinobservationgroup.Effect,painrelieftime,paindisappeartime,STsegmentdownrangeandTwaveinversionrangewascomparedintwogoupsrespectively.ResultsTotaleffectiverateinobservationgroupwashigherthanthatincontrolg5、roup,withstatisticaldifference(P<0.05).Painrelieftimeandpaindisappeartimeinobserva—tiongroupwasshorterthanthatincontrolgrouprespectively.Aftertreatment,STsegmentdownandTwaveinversionwasrecoveredrespectively,observationgroupwasbetterthancontrolgroup,withstatisticaldifference(P<0.05).Co6、nclu—sionLowmolecularheparincalciuminthetreatmentofunstableanginapectoriscanobtaingoodeffectandhighersafety,noobviousadversereaction,whichisworthyofexpansionandapplicationinclinic.【Keywords】Lowmolecularheparincalcium;Unstableanginapectoris;Efectobservation不稳定型心绞痛(unstableanginapectori7、s.UAP)1.2治疗方法是急性冠脉综合征的一种,介于稳定型心绞痛和急两组均给予硝酸酯类药物为基础治疗,根据病情性心肌梗死之间,如果处理不及时.易发展为急性心变化给予B一受体阻滞剂、肠溶阿司匹林、钙通道阻滞肌梗死。本文旨在探讨低分子肝素钙治疗UAP的效剂等。两组的药物使用剂量及时间无明显差异。观察果。组在上述治疗基础上加用低分子肝素钙(河北唐山生1资料与方法化药业股份有限公司,生产批号130801)0.4ml皮下1.1一般资料注射,2次/d,疗程为7d。用药前排除对肝素过敏、6选择本科2012年5月~2013年5月收治的UAP个月内有外伤或大手术史、脑出血、严重凝8、血障碍疾患
3、eopleSHospitalofJinanCity,Jinan250031,China【Abstract】0bjectiveTodiscussclinicaleffectoflowmolecularheparincalciuminthetreatmentofunstableanginapeetoris.Methods80patientswithdefinitediagnosisofunstableanginapectoriswererandomlydividedintotwogroups.eachgroupof40cases.Conventionaltreatme
4、ntwasusedincontrolgroup,onthebasisofcontrolgroup,lowmolecularheparincalciumwasusedinobservationgroup.Effect,painrelieftime,paindisappeartime,STsegmentdownrangeandTwaveinversionrangewascomparedintwogoupsrespectively.ResultsTotaleffectiverateinobservationgroupwashigherthanthatincontrolg
5、roup,withstatisticaldifference(P<0.05).Painrelieftimeandpaindisappeartimeinobserva—tiongroupwasshorterthanthatincontrolgrouprespectively.Aftertreatment,STsegmentdownandTwaveinversionwasrecoveredrespectively,observationgroupwasbetterthancontrolgroup,withstatisticaldifference(P<0.05).Co
6、nclu—sionLowmolecularheparincalciuminthetreatmentofunstableanginapectoriscanobtaingoodeffectandhighersafety,noobviousadversereaction,whichisworthyofexpansionandapplicationinclinic.【Keywords】Lowmolecularheparincalcium;Unstableanginapectoris;Efectobservation不稳定型心绞痛(unstableanginapectori
7、s.UAP)1.2治疗方法是急性冠脉综合征的一种,介于稳定型心绞痛和急两组均给予硝酸酯类药物为基础治疗,根据病情性心肌梗死之间,如果处理不及时.易发展为急性心变化给予B一受体阻滞剂、肠溶阿司匹林、钙通道阻滞肌梗死。本文旨在探讨低分子肝素钙治疗UAP的效剂等。两组的药物使用剂量及时间无明显差异。观察果。组在上述治疗基础上加用低分子肝素钙(河北唐山生1资料与方法化药业股份有限公司,生产批号130801)0.4ml皮下1.1一般资料注射,2次/d,疗程为7d。用药前排除对肝素过敏、6选择本科2012年5月~2013年5月收治的UAP个月内有外伤或大手术史、脑出血、严重凝
8、血障碍疾患
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